探索用功能化粒子耦合基质辅助激光解吸/电离质谱法检测指纹中的枪弹残留物

IF 3.6 3区 化学 Q2 CHEMISTRY, ANALYTICAL
Analyst Pub Date : 2024-11-05 DOI:10.1039/D4AN01260G
Sunil S. Adav, Yan Wen Crystal Tan, Choon Teck Low, Song Wei Loo, Ridhwan Yusoff, Archana Gautam, Yuk Lin Yong, Chiew Yung Yang, Chin Chin Lim and Kee Woei Ng
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引用次数: 0

摘要

在枪支法证调查中,检测枪击残留物(GSR)对于将枪支与嫌疑人联系起来以及确定射击距离以进行法证重建至关重要。基质辅助激光解吸附/电离飞行时间质谱(MALDI-ToF-MS)正在成为指纹分析的多功能和有前途的技术平台。功能化颗粒作为一种先进的除尘粉末,在潜伏指纹可视化方面的能力已得到广泛认可。本研究旨在探讨利用 MALDI-ToF-MS 使用功能化磁性指纹粉末区分普通指纹和 GSR 指纹的可行性,从而增强法医证据支持。在这项研究中,用苯基三乙氧基正硅酸盐(PTEOS)或 3-aminopropyl triethoxysilane(APTES)对二氧化硅和碳包覆的磁性氧化铁颗粒进行了表面功能化处理,分别制成疏水性和亲水性颗粒。使用这些功能化颗粒和 MALDI-ToF-MS 对捐献者的指纹(含 GSR 和普通指纹)进行了分析。结果表明,通过正交偏最小二乘判别分析,可以有效地将指纹可视化,并对含 GSR 的指纹和普通指纹进行确证判别。与传统方法相比,该技术灵敏度更高、速度更快、适应性更强,是潜伏指纹中 GSR 初步检测的理想选择。此外,在使用先进仪器进行全面分析后,它还有可能在法医调查中大大提高指纹证据的证明价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry

Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry

In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS) is emerging as a versatile and promising technological platform for fingerprint analysis. The capability of functionalized particles as an advanced dusting powder for visualizing latent fingerprints is widely recognized. This study aims to investigate the feasibility of employing functionalized magnetic fingerprint dusting powders for distinguishing regular and GSR fingerprints using MALDI-ToF-MS, thereby enhancing forensic evidentiary support. In this study, silica and carbon coated magnetic iron oxide particles were surface functionalized with phenyltriethoxy orthosilicate (PTEOS) or 3-aminopropyl triethoxysilane (APTES) to create hydrophobic and hydrophilic particles, respectively. Donor shooters’ fingerprints, both GSR-containing and regular, were analyzed using these functionalized particles coupled with MALDI-ToF-MS. The results demonstrated effective fingerprint visualization and conclusive discrimination between GSR-containing and regular fingerprints through orthogonal partial least squares discriminant analysis. This technique provides enhanced sensitivity, speed, and adaptability compared to conventional methods, making it a promising choice for initial detection of GSR in latent fingerprints. Moreover, when subjected to thorough analysis using advanced instruments, it has the potential to significantly strengthen the probative value of fingerprint evidence in forensic investigations.

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来源期刊
Analyst
Analyst 化学-分析化学
CiteScore
7.80
自引率
4.80%
发文量
636
审稿时长
1.9 months
期刊介绍: "Analyst" journal is the home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences.
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