Thiago Guedes Pinto, Thayza Aires Dias, Patricia Ramos Cury, Ana Claudia Muniz Renno, Glenda Nicioli da Silva, Daniel Araki Ribeiro
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引用次数: 0
摘要
本系统综述通过分析多项研究，重点试图回答以下问题：微核试验是否适合对接触麻醉气体的工人进行遗传生物监测？我们于 2023 年 12 月在 PubMed、SCOPUS 和 Web of Science 上进行了检索，以确定符合条件的文章。经过筛选，共有 18 篇文章被纳入综述。在质量评估中，共有 12 项研究被评为 "强"，3 项研究被评为 "中"，3 项研究被评为 "弱"。总的来说，研究结果表明，职业暴露于不同的麻醉剂可能会导致基因组损伤，而微核试验似乎是一种可靠且适用于长期暴露于麻醉剂的专业人员的 DNA 损伤生物标志物。
Is the micronucleus assay suitable for genetic biomonitoring of workers exposed to anesthetic gases? A systematic review.
The present systematic review, through the analysis of several studies, focused on attempting to answer the following question: Is the micronucleus assay suitable for genetic biomonitoring of workers exposed to anesthetic gases? We conducted searches in PubMed, SCOPUS and Web of Science to identify eligible articles on December, 2023. After screening the manuscript, a total of 18 articles were included in the review. In the quality assessment, a total of 12 studies were rated as strong, 3 studies were rated as moderate and 3 were rated as weak. Taken as a whole, the results suggest that occupational exposure to different anesthetic agents may induce genome damage and that the micronucleus assay appears to be a reliable and suitable DNA damage biomarker for professionals chronically exposed to anesthetics.
期刊介绍：
International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.
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