Zenhwa Ouyang, Daniel Joffe, J Scott Weese, Theresa Bernardo, Aimee Porter, Stephanie Villemaire, Marie-Eve Cardin, Ken Langelier, Jamie Mcgill-Worsley, Karren Prost, Zvonimir Poljak
{"title":"犬呼吸道传染病复合病的风险因素以及与该疾病相关的病原体。","authors":"Zenhwa Ouyang, Daniel Joffe, J Scott Weese, Theresa Bernardo, Aimee Porter, Stephanie Villemaire, Marie-Eve Cardin, Ken Langelier, Jamie Mcgill-Worsley, Karren Prost, Zvonimir Poljak","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Canine infectious respiratory disease complex (CIRDC) is a common respiratory condition typically associated with high-density populations.</p><p><strong>Objectives: </strong>The objectives of this study were to determine the most common pathogens involved in CIRDC and to identify risk factors (pathogens, environmental exposures) associated with the diagnosis.</p><p><strong>Animals and procedure: </strong>A prospective, multi-clinic, case-control study was conducted in Canada from April 2017 to May 2018. A total of 110 dogs (74 cases, 36 controls) were enrolled by participating veterinary clinics. Pathogens were detected using a respiratory PCR panel.</p><p><strong>Results: </strong>Canine parainfluenza virus (CPIV), <i>Bordetella bronchiseptica</i>, and canine respiratory coronavirus (CRCoV) were detected in cases only. According to 2 logistic regression models, detection of CPIV (OR: 14.42; 95% CI: 2.24 to ∞) and CRCoV (OR: 8.64; 95% CI: 1.26 to ∞) were associated with CIRDC disease status. In another model, exposures to multiple-dog gatherings also increased the odds (OR: 3.39; 95% CI: 1.26 to 9.81) of CIRDC diagnosis.</p><p><strong>Conclusions: </strong>Consistent with other studies, this study determined that CPIV, CRCoV, and <i>B. bronchiseptica</i> were important contributors to CIRDC cases. Detection of CPIV and CRCoV and exposure to areas of dog gatherings were identified as having a role in disease status when evaluated statistically, under the conditions of this study.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486139/pdf/","citationCount":"0","resultStr":"{\"title\":\"Risk factors for canine infectious respiratory disease complex and the pathogens associated with the disease.\",\"authors\":\"Zenhwa Ouyang, Daniel Joffe, J Scott Weese, Theresa Bernardo, Aimee Porter, Stephanie Villemaire, Marie-Eve Cardin, Ken Langelier, Jamie Mcgill-Worsley, Karren Prost, Zvonimir Poljak\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Canine infectious respiratory disease complex (CIRDC) is a common respiratory condition typically associated with high-density populations.</p><p><strong>Objectives: </strong>The objectives of this study were to determine the most common pathogens involved in CIRDC and to identify risk factors (pathogens, environmental exposures) associated with the diagnosis.</p><p><strong>Animals and procedure: </strong>A prospective, multi-clinic, case-control study was conducted in Canada from April 2017 to May 2018. A total of 110 dogs (74 cases, 36 controls) were enrolled by participating veterinary clinics. Pathogens were detected using a respiratory PCR panel.</p><p><strong>Results: </strong>Canine parainfluenza virus (CPIV), <i>Bordetella bronchiseptica</i>, and canine respiratory coronavirus (CRCoV) were detected in cases only. According to 2 logistic regression models, detection of CPIV (OR: 14.42; 95% CI: 2.24 to ∞) and CRCoV (OR: 8.64; 95% CI: 1.26 to ∞) were associated with CIRDC disease status. In another model, exposures to multiple-dog gatherings also increased the odds (OR: 3.39; 95% CI: 1.26 to 9.81) of CIRDC diagnosis.</p><p><strong>Conclusions: </strong>Consistent with other studies, this study determined that CPIV, CRCoV, and <i>B. bronchiseptica</i> were important contributors to CIRDC cases. Detection of CPIV and CRCoV and exposure to areas of dog gatherings were identified as having a role in disease status when evaluated statistically, under the conditions of this study.</p>\",\"PeriodicalId\":9429,\"journal\":{\"name\":\"Canadian Veterinary Journal-revue Veterinaire Canadienne\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486139/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Veterinary Journal-revue Veterinaire Canadienne\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Veterinary Journal-revue Veterinaire Canadienne","FirstCategoryId":"97","ListUrlMain":"","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Risk factors for canine infectious respiratory disease complex and the pathogens associated with the disease.
Background: Canine infectious respiratory disease complex (CIRDC) is a common respiratory condition typically associated with high-density populations.
Objectives: The objectives of this study were to determine the most common pathogens involved in CIRDC and to identify risk factors (pathogens, environmental exposures) associated with the diagnosis.
Animals and procedure: A prospective, multi-clinic, case-control study was conducted in Canada from April 2017 to May 2018. A total of 110 dogs (74 cases, 36 controls) were enrolled by participating veterinary clinics. Pathogens were detected using a respiratory PCR panel.
Results: Canine parainfluenza virus (CPIV), Bordetella bronchiseptica, and canine respiratory coronavirus (CRCoV) were detected in cases only. According to 2 logistic regression models, detection of CPIV (OR: 14.42; 95% CI: 2.24 to ∞) and CRCoV (OR: 8.64; 95% CI: 1.26 to ∞) were associated with CIRDC disease status. In another model, exposures to multiple-dog gatherings also increased the odds (OR: 3.39; 95% CI: 1.26 to 9.81) of CIRDC diagnosis.
Conclusions: Consistent with other studies, this study determined that CPIV, CRCoV, and B. bronchiseptica were important contributors to CIRDC cases. Detection of CPIV and CRCoV and exposure to areas of dog gatherings were identified as having a role in disease status when evaluated statistically, under the conditions of this study.
期刊介绍：
The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health.
A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).
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