入院快速抗原检测（RATs）对从急症医院转入康复后环境的患者进行 COVID-19 检测的作用。

IF 3.8 3区医学 Q2 INFECTIOUS DISEASES

American journal of infection control Pub Date : 2024-11-01 DOI:10.1016/j.ajic.2024.10.031

Ann Gaffney MSc, PG Cert, RGN , Edmond G. Smyth MB, MsC, FRCPath, FRCPI , Zena Moore PhD, MSc, FFNMRCSI, PGDip, RGN , Declan Patton PhD, MSc, PGDipEd, PGCRM, BNS(Hons), RNT, RPN , Tom O' Connor RGN, RNT, Dip Nur, BSc, MSc Ad Nursing, PGDipEd, EdD , Rosemarie Derwin

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引用次数: 0

摘要

背景：快速抗原检测（RAT）适用于医疗点检测，无需实验室时间，并能立即得到结果。然而，在医疗机构中，与聚合酶链反应（PCR）检测相比，快速抗原检测对检测无症状的 COVID-19 感染是否有用？目的：本研究的目的是利用快速抗原检测实施可靠的检测系统，以便在从急诊医院转入急性期后康复病房（PARU）的主要无症状患者中快速检测 COVID-19 感染：方法：对入院后三个月内没有确诊Covid-19感染病史的所有新入院患者进行RAT检测。对所有 RAT 检测呈阳性的患者进行 PCR 检测，以进行确认。研究了 PCR 检测结果中 COVID-19 的周期阈值（Ct），以确定 RATs 的效用：2023年1月至12月，共有1403名患者转入PARU。研究结果显示，RATs 的准确率为 85%，入院时的假阴性结果率为 15%。所有在入院时RAT呈阳性的患者的PCR检测结果也都呈阳性：这种检测算法可及早发现并及时隔离阳性病例，从而减少 COVID-19 感染的传播、医院疫情爆发和病床/病房关闭的可能性。

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Role of admission rapid antigen testing (RATs) for COVID-19 on patients transferred from acute hospitals to a postacute rehabilitation setting

Background

Rapid antigen tests (RATs) are suitable for point-of-care testing, require no laboratory time, and give immediate results. However, are RATs useful for detecting asymptomatic COVID-19 infection when compared with polymerase chain reaction (PCR) testing in health care settings?

Methods

RAT testing was carried out on all new admissions without a history of confirmed COVID-19 infection within 3 months of admission. PCR testing was carried out on all patients with a positive RAT for confirmation purposes. The cycle threshold values of COVID-19-detected results on PCR testing were examined to determine the utility of the RATs.

Results

A total of 1,403 patients were transferred to the postacute rehabilitation unit from January to December 2023. The results of the study revealed an 85% accuracy of RATs with a 15% rate of false-negative results at the time of admission. All patients who had a positive RAT at the time of admission also had a positive PCR test.

Conclusions

This testing algorithm resulted in early detection and prompt isolation of positive cases reducing the likely spread of COVID-19 infection, hospital outbreaks, and bed/ward closures.

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)