以 AgSCF3 为媒介的苯并咪唑衍生物的银介导自由基级联三氟甲基硫代化/环化反应。

IF 2.9 3区 化学 Q1 CHEMISTRY, ORGANIC
Pan Liu, Yang Geng, Dapeng Zou, Yangjie Wu, Yusheng Wu
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引用次数: 0

摘要

研究了银介导的未活化烯烃的级联三氟甲基硫代/环化反应。该策略采用 AgSCF3 作为三氟甲基硫代试剂,以合理的产率获得了多种有用的三氟甲基硫代三环咪唑衍生物。初步的机理研究表明,本反应是通过自由基过程进行的。该方法具有原子经济性、广泛的官能团兼容性、操作简便性和产品多样性等特点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Silver-mediated radical cascade trifluoromethylthiolation/cyclization of benzimidazole derivatives with AgSCF3.

A silver-mediated cascade trifluoromethylthiolation/cyclization of unactivated alkenes has been investigated. This strategy employs AgSCF3 as the trifluoromethylthiolating reagent to obtain a variety of useful trifluoromethylthiolated tricyclic imidazol derivatives in reasonable yields. Preliminary mechanistic studies indicate that the present reaction takes place via a radical process. This method is distinguished by its atom economy, wide functional group compatibility, operational simplicity and product diversity.

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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: The international home of synthetic, physical and biomolecular organic chemistry.
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