[金]/[银]催化的非水解 C-糖苷的合成。

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2024-10-23 DOI:10.1039/D4OB01339E

Saptashwa Chakraborty, Daksh Telang, Bijoyananda Mishra and Srinivas Hotha

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引用次数: 0

摘要

在天然产物、药物和小分子探针中发现了许多 C-糖苷。在此，我们报告了通过[Au]/[Ag]催化活化乙炔基环己糖基碳酸酯供体合成 C-糖苷的过程。这种温和、催化、快速、高产的方法可以合成多种多样的 C-糖苷，而这些糖苷的合成在其他方法中是很难实现的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

[Au]/[Ag]-catalysed synthesis of non-hydrolysable C-glycosides†

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[Au]/[Ag]-catalysed synthesis of non-hydrolysable C-glycosides†

Many C-glycosides are found in natural products, drugs and small molecular probes. Herein, we report the synthesis of C-glycosides by the [Au]/[Ag]-catalysed activation of ethynylcyclohexyl glycosyl carbonate donors. This mild, catalytic, fast and high yielding protocol enables the synthesis of a diverse array of C-glycosides that were otherwise challenging to synthesize.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.