硬膜外侵犯与喉鳞状细胞癌：系统综述。

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology Pub Date : 2024-11-01 DOI:10.1016/j.bjorl.2024.101519

Debora Modelli Vianna Ocampo Quintana , Rogerio Aparecido Dedivitis , Luiz Paulo Kowalski

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引用次数: 0

摘要

研究目的有几项研究评估了喉癌神经周围侵犯（IPN）的预后意义，但结果尚无定论。因此，我们进行了一项荟萃分析，旨在确定 IPN 在喉癌中的预后价值：方法：通过PubMed、Scielo、Lilacs、Cochrane和Websco检索MedLine，进行文献综述。统计分析使用 RevMan 5.4：结果：共纳入 19 项喉癌研究。结果显示，IPN在喉癌中的2年生存率为RR 0.71（0.59-0.86）；无病生存率为RR 0.51（0.14-1.95）；局部复发率为RR 1.71（1.25-2.35）：结论：IPN是喉癌的不良预后因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Perineural invasion and laryngeal squamous cell carcinoma: a systematic review

Objectives

Several studies have evaluated the prognostic significance of Perineural Invasion (IPN) in laryngeal cancer; however, the results are non-conclusive. Therefore, we conducted a meta-analysis aiming to identify the prognostic value of IPN in laryngeal cancer.

Methods

A literature review was performed, searching MedLine via PubMed, Scielo, Lilacs, Cochrane and Websco. RevMan 5.4 was used for the statistical analysis.

Results

A total of 19 laryngeal cancer studies were included. The results indicate that IPN in laryngeal cancer shows 2-year survival with RR 0.71 (0.59‒0.86); disease-free survival RR 0.51 (0.14–1.95); and locoregional recurrence RR 1.71 (1.25–2.35).

Conclusion

IPN is a negative prognostic factor in laryngeal cancer.

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来源期刊

Brazilian Journal of Otorhinolaryngology OTORHINOLARYNGOLOGY-

CiteScore

3.00

自引率

0.00%

发文量

205

审稿时长

4-8 weeks

期刊介绍： Brazilian Journal of Otorhinolaryngology publishes original contributions in otolaryngology and the associated areas (cranio-maxillo-facial surgery and phoniatrics). The aim of this journal is the national and international divulgation of the scientific production interesting to the otolaryngology, as well as the discussion, in editorials, of subjects of scientific, academic and professional relevance. The Brazilian Journal of Otorhinolaryngology is born from the Revista Brasileira de Otorrinolaringologia, of which it is the English version, created and indexed by MEDLINE in 2005. It is the official scientific publication of the Brazilian Association of Otolaryngology and Cervicofacial Surgery. Its abbreviated title is Braz J Otorhinolaryngol., which should be used in bibliographies, footnotes and bibliographical references and strips.