{"title":"利用弹道凝胶作为组织替代物,对用于白细胞校准的新型 3D 打印模型进行蒙特卡洛建模和模拟。","authors":"","doi":"10.1016/j.apradiso.2024.111565","DOIUrl":null,"url":null,"abstract":"<div><div>Whole-body counter (WBC) systems are used for <em>in vivo</em> monitoring in occupational internal dosimetry, typically calibrated using physical anthropomorphic phantoms. Our research group previously 3D-printed the Reference Female Phantom for Internal Dosimetry (RFPID) without internal organs specifically designed for WBC calibration. The RFPID and it is intended to fill it homogenously with ballistic gel, which is commonly used as a tissue equivalent in ballistic studies. However, comprehensive characterization of its physicochemical properties and radiological behavior as a tissue surrogate for dosimetry is limited. This study aims to evaluate the suitability of ballistic gel as a tissue substitute for physical phantoms in WBC system calibration and to analyze the RFPID as a model for WBC calibration. Ballistic gel tests determined its density and attenuation coefficients, comparing it to muscle, water, and PMMA. The RFPID was modeled and simulated using MCNP6.2 code and placed in an <em>in vivo</em> monitoring system using an 8”x4″ NaI(Tl) scintillator detector previously validated. The simulations were repeated with the RCP_AF of ICRP-110. Results indicate that ballistic gel has a density approximately 6% different from muscle and shows similar linear attenuation coefficients to muscle at intermediate and high energy levels (186–2200 keV). Simulations revealed a disparity of less than 9% in counting efficiency between RFPID and RCP_AF for energies from 100 to 3000 keV, confirming the phantom's suitability for WBC calibration and ballistic gel's viability as a tissue surrogate in internal dosimetry.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Monte Carlo modeling and simulation of a new 3D printed phantom for WBC calibration with ballistic gel as a tissue substitute\",\"authors\":\"\",\"doi\":\"10.1016/j.apradiso.2024.111565\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Whole-body counter (WBC) systems are used for <em>in vivo</em> monitoring in occupational internal dosimetry, typically calibrated using physical anthropomorphic phantoms. Our research group previously 3D-printed the Reference Female Phantom for Internal Dosimetry (RFPID) without internal organs specifically designed for WBC calibration. The RFPID and it is intended to fill it homogenously with ballistic gel, which is commonly used as a tissue equivalent in ballistic studies. However, comprehensive characterization of its physicochemical properties and radiological behavior as a tissue surrogate for dosimetry is limited. This study aims to evaluate the suitability of ballistic gel as a tissue substitute for physical phantoms in WBC system calibration and to analyze the RFPID as a model for WBC calibration. Ballistic gel tests determined its density and attenuation coefficients, comparing it to muscle, water, and PMMA. The RFPID was modeled and simulated using MCNP6.2 code and placed in an <em>in vivo</em> monitoring system using an 8”x4″ NaI(Tl) scintillator detector previously validated. The simulations were repeated with the RCP_AF of ICRP-110. Results indicate that ballistic gel has a density approximately 6% different from muscle and shows similar linear attenuation coefficients to muscle at intermediate and high energy levels (186–2200 keV). Simulations revealed a disparity of less than 9% in counting efficiency between RFPID and RCP_AF for energies from 100 to 3000 keV, confirming the phantom's suitability for WBC calibration and ballistic gel's viability as a tissue surrogate in internal dosimetry.</div></div>\",\"PeriodicalId\":8096,\"journal\":{\"name\":\"Applied Radiation and Isotopes\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Radiation and Isotopes\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0969804324003932\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Radiation and Isotopes","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969804324003932","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Monte Carlo modeling and simulation of a new 3D printed phantom for WBC calibration with ballistic gel as a tissue substitute
Whole-body counter (WBC) systems are used for in vivo monitoring in occupational internal dosimetry, typically calibrated using physical anthropomorphic phantoms. Our research group previously 3D-printed the Reference Female Phantom for Internal Dosimetry (RFPID) without internal organs specifically designed for WBC calibration. The RFPID and it is intended to fill it homogenously with ballistic gel, which is commonly used as a tissue equivalent in ballistic studies. However, comprehensive characterization of its physicochemical properties and radiological behavior as a tissue surrogate for dosimetry is limited. This study aims to evaluate the suitability of ballistic gel as a tissue substitute for physical phantoms in WBC system calibration and to analyze the RFPID as a model for WBC calibration. Ballistic gel tests determined its density and attenuation coefficients, comparing it to muscle, water, and PMMA. The RFPID was modeled and simulated using MCNP6.2 code and placed in an in vivo monitoring system using an 8”x4″ NaI(Tl) scintillator detector previously validated. The simulations were repeated with the RCP_AF of ICRP-110. Results indicate that ballistic gel has a density approximately 6% different from muscle and shows similar linear attenuation coefficients to muscle at intermediate and high energy levels (186–2200 keV). Simulations revealed a disparity of less than 9% in counting efficiency between RFPID and RCP_AF for energies from 100 to 3000 keV, confirming the phantom's suitability for WBC calibration and ballistic gel's viability as a tissue surrogate in internal dosimetry.
期刊介绍:
Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria.
Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.