Alaa Baik, Najlaa Alamoudi, Osama Felemban, Azza El-Housseiny, Eman Almabadi, Khadijah Baik, Amani Altuwirqi, Ibrahim Masoud
{"title":"使用 VanishTM XT 预防咬合面龋齿：一项为期 18 个月的随访随机临床试验。","authors":"Alaa Baik, Najlaa Alamoudi, Osama Felemban, Azza El-Housseiny, Eman Almabadi, Khadijah Baik, Amani Altuwirqi, Ibrahim Masoud","doi":"10.1186/s12903-024-05095-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the effectiveness of a light curable resin-modified glass ionomer varnish (Vanish<sup>TM</sup> XT) in the prevention of occlusal caries compared to topical fluoride varnish in newly erupted first permanent molars over 18 months.</p><p><strong>Methods: </strong>A randomized controlled clinical trial was conducted using a split-mouth design. A total of 53 participants aged 6-9 years with 97 pairs of caries-free newly erupted first permanent molars were enrolled in the study. Each molar in the pair was randomly assigned either to the experimental group, which received the Vanish<sup>TM</sup> XT Extended Contact Varnish, or to the control group, which received topical fluoride varnish (Vanish<sup>TM</sup> 5% Sodium Fluoride White Varnish). Follow-ups were performed at 6, 12, and 18 months to evaluate dental caries development.</p><p><strong>Results: </strong>At the 6-month follow-up, caries development was significantly higher in the control group (7.8%) than that in the experimental group (0%) (P = 0.031). At the 12-month follow-up, significantly (P = 0.012) more occlusal caries developed in the control group (12.2%) compared to the experimental group (1.2%). At the 18-month follow-up, significantly (P = 0.002) more occlusal caries developed in the control group (14.3%) compared to the experimental group (1.1%).</p><p><strong>Conclusion: </strong>Compared to fluoride varnish, Vanish<sup>TM</sup> XT was significantly more effective in preventing caries on the occlusal surfaces of newly erupted first permanent molars at 6, 12, and 18 months.</p><p><strong>Trial registration: </strong>Registration number at ClinicalTrials.gov: NCT04579536 on 08/10/ 2020, retrospectively registered.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1328"},"PeriodicalIF":2.6000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529266/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevention of occlusal caries using Vanish<sup>TM</sup> XT: an 18-month follow-up randomized clinical trial.\",\"authors\":\"Alaa Baik, Najlaa Alamoudi, Osama Felemban, Azza El-Housseiny, Eman Almabadi, Khadijah Baik, Amani Altuwirqi, Ibrahim Masoud\",\"doi\":\"10.1186/s12903-024-05095-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To evaluate the effectiveness of a light curable resin-modified glass ionomer varnish (Vanish<sup>TM</sup> XT) in the prevention of occlusal caries compared to topical fluoride varnish in newly erupted first permanent molars over 18 months.</p><p><strong>Methods: </strong>A randomized controlled clinical trial was conducted using a split-mouth design. A total of 53 participants aged 6-9 years with 97 pairs of caries-free newly erupted first permanent molars were enrolled in the study. Each molar in the pair was randomly assigned either to the experimental group, which received the Vanish<sup>TM</sup> XT Extended Contact Varnish, or to the control group, which received topical fluoride varnish (Vanish<sup>TM</sup> 5% Sodium Fluoride White Varnish). Follow-ups were performed at 6, 12, and 18 months to evaluate dental caries development.</p><p><strong>Results: </strong>At the 6-month follow-up, caries development was significantly higher in the control group (7.8%) than that in the experimental group (0%) (P = 0.031). At the 12-month follow-up, significantly (P = 0.012) more occlusal caries developed in the control group (12.2%) compared to the experimental group (1.2%). At the 18-month follow-up, significantly (P = 0.002) more occlusal caries developed in the control group (14.3%) compared to the experimental group (1.1%).</p><p><strong>Conclusion: </strong>Compared to fluoride varnish, Vanish<sup>TM</sup> XT was significantly more effective in preventing caries on the occlusal surfaces of newly erupted first permanent molars at 6, 12, and 18 months.</p><p><strong>Trial registration: </strong>Registration number at ClinicalTrials.gov: NCT04579536 on 08/10/ 2020, retrospectively registered.</p>\",\"PeriodicalId\":9072,\"journal\":{\"name\":\"BMC Oral Health\",\"volume\":\"24 1\",\"pages\":\"1328\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529266/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Oral Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12903-024-05095-8\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Oral Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12903-024-05095-8","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Prevention of occlusal caries using VanishTM XT: an 18-month follow-up randomized clinical trial.
Aim: To evaluate the effectiveness of a light curable resin-modified glass ionomer varnish (VanishTM XT) in the prevention of occlusal caries compared to topical fluoride varnish in newly erupted first permanent molars over 18 months.
Methods: A randomized controlled clinical trial was conducted using a split-mouth design. A total of 53 participants aged 6-9 years with 97 pairs of caries-free newly erupted first permanent molars were enrolled in the study. Each molar in the pair was randomly assigned either to the experimental group, which received the VanishTM XT Extended Contact Varnish, or to the control group, which received topical fluoride varnish (VanishTM 5% Sodium Fluoride White Varnish). Follow-ups were performed at 6, 12, and 18 months to evaluate dental caries development.
Results: At the 6-month follow-up, caries development was significantly higher in the control group (7.8%) than that in the experimental group (0%) (P = 0.031). At the 12-month follow-up, significantly (P = 0.012) more occlusal caries developed in the control group (12.2%) compared to the experimental group (1.2%). At the 18-month follow-up, significantly (P = 0.002) more occlusal caries developed in the control group (14.3%) compared to the experimental group (1.1%).
Conclusion: Compared to fluoride varnish, VanishTM XT was significantly more effective in preventing caries on the occlusal surfaces of newly erupted first permanent molars at 6, 12, and 18 months.
Trial registration: Registration number at ClinicalTrials.gov: NCT04579536 on 08/10/ 2020, retrospectively registered.
期刊介绍：
BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
