Tyler J Murphy, Elizabeth D Krebs, Derek A Riffert, Ronnie Mubang, Mina F Nordness, Christopher Guidry, Stephen Gondek, Robel T Beyene
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引用次数: 0
摘要
诊断烧伤患者烟雾吸入性损伤的标准方法是支气管镜检查,同时进行或不进行支气管肺泡灌洗。然而,在已有的文献中,与这些程序相关的风险描述很少。我们试图研究烧伤患者入院时进行诊断性支气管肺泡灌洗与肺炎发生之间的关系。这项对插管烧伤患者的回顾性分析研究了入院时接受支气管镜检查的患者,并对接受支气管肺泡灌洗和未接受支气管肺泡灌洗的患者进行了比较。人口统计学和基线特征采用卡方检验或学生 t 检验进行分析。未调整和多变量逻辑回归研究评估了入院支气管肺泡灌洗对肺炎发生的影响。在接受支气管镜检查的 196 名患者中,有 98 人符合我们的分析标准。接受支气管肺泡灌洗的患者更可能是男性,且简易损伤评分等级更高。在未调整和多变量逻辑回归模型中,接受支气管肺泡灌洗的患者更有可能在入院期间患上肺炎。这些患者的住院时间也更长,使用呼吸机的天数更多,而且更有可能接受第二次支气管镜检查。这些研究结果表明,入院支气管肺泡灌洗与住院期间肺炎风险增加有关,建议烧伤患者在入院进行支气管镜检查时谨慎使用支气管肺泡灌洗。
Incidence of Pneumonia following Bronchoscopy and Bronchoalveolar Lavage in Burn Patients.
The standard modality for diagnosis of smoke inhalational injury in burn patients is bronchoscopy with or without bronchoalveolar lavage. However, the risks associated with these procedures are poorly described in established literature. We sought to investigate the association between diagnostic bronchoalveolar lavage at admission and the development of pneumonia in burn patients. This retrospective analysis of intubated burn patients studied those who underwent bronchoscopy on admission, comparing patients who received bronchoalveolar lavage to those who did not. Demographics and baseline characteristics were analyzed using chi-squared or Student's t-test. Unadjusted and multivariable logistic regression studies assessed the effect of admission bronchoalveolar lavage on development of pneumonia. Out of the 196 patients who underwent bronchoscopy, 98 met our criteria for analysis. The bronchoalveolar lavage group was more likely to be male and have a higher grade of abbreviated injury score. Patients who received bronchoalveolar lavage were more likely to develop pneumonia during the admission in both unadjusted and multivariable logistic regression models. These patients also had a longer hospital length of stay, greater number of ventilator days, and were more likely to undergo second bronchoscopy. These findings associate admission bronchoalveolar lavage with increased risk of pneumonia during the index hospitalization, suggesting a judicious use of bronchoalveolar lavage during admission bronchoscopy in burn patients.
期刊介绍:
Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.