埃塞俄比亚西奥罗米亚成人心脏病患者的高尿酸血症及相关因素。

IF 2.3 Q3 NUTRITION & DIETETICS
Nutrition and Metabolic Insights Pub Date : 2024-10-16 eCollection Date: 2024-01-01 DOI:10.1177/11786388241288668
Bedasa Addisu, Asnakew Tesfahun Sefew, Abiyu Milkit, Amanuel Hika, Amanuel Kelem, Agete Tadewos Hirigo
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引用次数: 0

摘要

背景:由于内皮功能障碍、胰岛素抵抗和无氧自由基生成增加等因素,高尿酸血症患者罹患心血管疾病的风险增加。然而,有关埃塞俄比亚成人心脏病患者高尿酸血症患病率和预测因素的数据却很有限:2022年6月至9月,在安博大学转诊医院对269名参与者进行了横断面研究。通过方便抽样获得了参与者的人口统计学特征和相关数据。高尿酸血症根据制造商的截止标准进行定义。数据录入和分析使用 SPSS 25 进行。采用二元逻辑回归模型评估了结果与解释变量之间的关联:研究参与者中,56.9%为男性。参与者的平均年龄为 51.1 岁(±15.8)。高尿酸血症患病率为 43.1%(95% CI:37.1-49.1)。男性的高尿酸血症患病率明显高于女性(23.4% vs 19.7%,P = .026)。男性患高尿酸血症的几率是女性的 2.9 倍。发现体重指数⩾30 kg/m2、年龄⩾54 岁和男性与高尿酸血症患病率有显著关联,调整后的几率比(95% CI)分别为 2.3 (1.7-5.2)、2.9 (2.2-5.9) 和 3.56 (2.1-12.8)。此外,吸烟、血脂异常和腰围也与高尿酸血症的患病率显著相关:结论:研究中近一半的心脏病患者被诊断出患有高尿酸血症。这些发现强调了早期识别和治疗高尿酸血症以及调整生活方式和行为对维持这一特殊人群的生活质量的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hyperuricemia and Associated Factors in Adult Cardiac Patients in Western Oromia, Ethiopia.

Background: Individuals who have hyperuricemia are at increased risk of cardiovascular diseases due to factors such as endothelial dysfunction, insulin resistance, and increased production of oxygen-free radicals. However, data on the prevalence and predictors of hyperuricemia among adults with cardiac diseases in Ethiopia are limited.

Methods: A cross-sectional study was conducted on 269 participants at the Ambo University referral hospital from June to September, 2022. Participant demographics and relevant data were obtained through convenient sampling. Hyperuricemia was defined according to the manufacturer's cutoff criteria. Data entry and analysis were conducted using SPSS 25. The association between the outcome and explanatory variables was assessed using a binary logistic regression model.

Results: Of the study participants, 56.9% were male. The mean age of participants was 51.1 years (±15.8). The prevalence of hyperuricemia was 43.1% (95% CI: 37.1-49.1). Males presented a significantly higher prevalence of hyperuricemia compared to females (23.4% vs 19.7%, P = .026). Males had 2.9 times higher odds of hyperuricemia compared to females. Significant associations with the prevalence of hyperuricemia were found for individuals with a BMI ⩾30 kg/m2, age ⩾54 years, and male gender, with adjusted odds ratios (95% CI) of 2.3 (1.7-5.2), 2.9 (2.2-5.9), and 3.56 (2.1-12.8), respectively. Additionally, smoking, dyslipidemia, and waist circumference were also significantly associated with the prevalence of hyperuricemia.

Conclusions: Nearly half of the cardiac patients in the study were diagnosed with hyperuricemia. These findings underscores the importance of early identification and treatment of hyperuricemia, alongside lifestyle and behavioral modifications, to maintain the quality of life in this specific population.

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来源期刊
Nutrition and Metabolic Insights
Nutrition and Metabolic Insights NUTRITION & DIETETICS-
CiteScore
3.30
自引率
0.00%
发文量
27
审稿时长
8 weeks
期刊介绍: Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
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