新生儿凝血功能障碍。

Q2 Medicine

NeoReviews Pub Date : 2024-11-01 DOI:10.1542/neo.25-11-e694

Lorena Ostilla, Karyssa Knopoff, Patrick Myers, Perry Morocco

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引用次数: 0

摘要

新生儿的凝血系统不同于儿童和成人，许多循环止血因子在新生儿中含量较低。婴儿也很容易受到孕妇体内影响凝血系统的疾病和病症的影响，因此很难快速确定新生儿凝血功能障碍的原因。凝血功能障碍可导致婴儿高发病率和高死亡率，因此早期诊断和及时治疗至关重要。本综述概述了常见和不常见的新生儿先天性和后天性凝血病的临床特点、诊断和管理、流行病学和病因。

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Disorders of Coagulation in the Newborn.

The coagulation system in newborns varies from that of children and adults, with many circulating hemostatic factors being lower in the newborn. Infants are also susceptible to diseases and conditions in the pregnant person affecting their coagulation system, which can make it difficult to rapidly identify the cause behind coagulopathy in a neonate. Coagulation disorders can result in high levels of infant morbidity and mortality, which makes early diagnosis and prompt treatment critical. This review outlines the clinical characteristics, diagnosis and management, epidemiology, and etiologies of both common and uncommon congenital and acquired forms of neonatal coagulopathy.

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来源期刊

NeoReviews Medicine-Pediatrics, Perinatology and Child Health

CiteScore

2.20

自引率

0.00%

发文量

110

期刊介绍： Co-edited by Alistair G.S. Philip, MD, FAAP, and William W. Hay Jr., MD, FAAP, NeoReviews each month delivers 3 to 4 clinical reviews, case discussions, basic science insights and "on the horizon" pieces. Written and edited by experts, these concise reviews are available to NeoReviews subscribers at http://neoreviews.aappublications.org. Since January 2009, all clinical articles have been mapped to the American Board of Pediatrics (ABP) content specifications in neonatology.