{"title":"泰国 Sai-Nam-Phueng 橘副产品的绿色化学 (1)：利用响应面方法、抗氧化剂和细胞毒性回收有价值的生物活性化合物来源","authors":"Kanchanok Kodchakorn , Prachya Kongtawelert","doi":"10.1016/j.wmb.2024.10.004","DOIUrl":null,"url":null,"abstract":"<div><div><em>Citrus reticulata</em> Blanco, specifically Sai-Nam-Phueng orange traditionally considered by-products, are rich in phytochemicals — limonoids, flavonoids. This study compared seeds and peels for the phytochemical content and antioxidant activity. Using single-factor experiments and response surface methodology (RSM), the effects of ethanol concentration, solvent-to-solid ratio, and temperature on extract yield were optimized. The study found optimal conditions to be 70.50 % ethanol, 28.11 mL/g solvent-to-solid ratio, and 69.99 °C. Experimental values are in reasonable agreement with predicted values. Phytochemical contents were characterized using HPLC, mass spectrometry, and NMR spectroscopy, successfully demonstrating efficient of purified compounds from orange by-products and cost-effective extraction methods.</div><div><strong>Kewords:</strong> Antioxidant, Green-extractions, Phytochemicals, Response Surface Methodology, Cytotoxicity.</div></div>","PeriodicalId":101276,"journal":{"name":"Waste Management Bulletin","volume":"2 4","pages":"Pages 108-122"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Green-chemistry of by-products from Sai-Nam-Phueng orange in Thailand (1): Recovering a valuable source of bioactive compounds using response surface methodology, antioxidant, and cytotoxicity\",\"authors\":\"Kanchanok Kodchakorn , Prachya Kongtawelert\",\"doi\":\"10.1016/j.wmb.2024.10.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>Citrus reticulata</em> Blanco, specifically Sai-Nam-Phueng orange traditionally considered by-products, are rich in phytochemicals — limonoids, flavonoids. This study compared seeds and peels for the phytochemical content and antioxidant activity. Using single-factor experiments and response surface methodology (RSM), the effects of ethanol concentration, solvent-to-solid ratio, and temperature on extract yield were optimized. The study found optimal conditions to be 70.50 % ethanol, 28.11 mL/g solvent-to-solid ratio, and 69.99 °C. Experimental values are in reasonable agreement with predicted values. Phytochemical contents were characterized using HPLC, mass spectrometry, and NMR spectroscopy, successfully demonstrating efficient of purified compounds from orange by-products and cost-effective extraction methods.</div><div><strong>Kewords:</strong> Antioxidant, Green-extractions, Phytochemicals, Response Surface Methodology, Cytotoxicity.</div></div>\",\"PeriodicalId\":101276,\"journal\":{\"name\":\"Waste Management Bulletin\",\"volume\":\"2 4\",\"pages\":\"Pages 108-122\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Waste Management Bulletin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949750724000889\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Waste Management Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949750724000889","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Green-chemistry of by-products from Sai-Nam-Phueng orange in Thailand (1): Recovering a valuable source of bioactive compounds using response surface methodology, antioxidant, and cytotoxicity
Citrus reticulata Blanco, specifically Sai-Nam-Phueng orange traditionally considered by-products, are rich in phytochemicals — limonoids, flavonoids. This study compared seeds and peels for the phytochemical content and antioxidant activity. Using single-factor experiments and response surface methodology (RSM), the effects of ethanol concentration, solvent-to-solid ratio, and temperature on extract yield were optimized. The study found optimal conditions to be 70.50 % ethanol, 28.11 mL/g solvent-to-solid ratio, and 69.99 °C. Experimental values are in reasonable agreement with predicted values. Phytochemical contents were characterized using HPLC, mass spectrometry, and NMR spectroscopy, successfully demonstrating efficient of purified compounds from orange by-products and cost-effective extraction methods.
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