一名儿童腹膜透析引起的腹膜炎:病例报告。

Biomedicine hub Pub Date : 2024-09-13 eCollection Date: 2024-01-01 DOI:10.1159/000541001
Tetsuya Sakaguchi, Hiroshi Tamura, Keishiro Furuie, Shohei Kuraoka, Hitoshi Nakazato
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引用次数: 0

摘要

简介:腹膜炎是腹膜透析(PD)的重要并发症:腹膜炎是腹膜透析(PD)的一个重要并发症。此外,在腹膜炎病情严重或病程较长的情况下,腹膜的结构和功能可能会发生变化,导致腹膜透析难以继续进行。因此,确定致病菌并尽早使用抗生素对降低治疗失败的风险至关重要。与此同时,由非结核分枝杆菌(NTM)引起的细菌性腹膜炎很难识别。非结核分枝杆菌也是最难根除的微生物之一。通常情况下,需要拔除腹腔导管并使用多种抗生素才能根除 NTM 感染:在此,我们报告了一例由福氏分枝杆菌引起的腹膜炎病例,患者是一名接受腹膜透析的 3 岁男孩。该患者曾有过由 fortuitum 分枝杆菌引起的最初腹膜透析导管出口部位感染病史,并导致腹膜透析相关性腹膜炎。因此,患者的导管被拔除,转为血液透析,并接受了多种抗生素治疗:结论:这种罕见的腹膜炎病因与高死亡率和严重的发病率相关,通常需要拔除腹膜透析导管并长期使用多种抗生素治疗。当腹膜透析导管周围(如溃疡处)出现 NTM 感染时,有必要拔除导管并转为血液透析,直至感染痊愈。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mycobacterium fortuitum Peritoneal Dialysis-Related Peritonitis in a Child: A Case Report.

Introduction: Peritonitis is a significant complication of peritoneal dialysis (PD). Additionally, in severe or prolonged cases of peritonitis, the structure and function of the peritoneum may change, making it difficult to continue PD. Thus, identifying the causative agent and early administration of antibiotics are essential to minimize the risk of treatment failure. Meanwhile, bacterial peritonitis caused by nontuberculous Mycobacteria (NTM) are difficult to identify. NTM are also among the most difficult organisms to eradicate. Oftentimes, removal of the peritoneal catheter and multiple antibiotics are required to eradicate NTM infections.

Case presentation: Herein, we report a case of peritonitis caused by Mycobacterium fortuitum in a 3-year-old boy undergoing PD. The patient had a history of an initial PD catheter exit site infection caused by M. fortuitum that led to PD-associated peritonitis. Consequently, the catheter was removed, and the patient was switched to hemodialysis and treated with multiple antibiotics.

Conclusion: This rare cause of peritonitis is associated with a high mortality and severe morbidity and usually requires removal of the PD catheter as well as prolonged treatment with multiple antibiotics. When there is NTM infection around the PD catheter, such as in an ulcer, it is necessary to remove the catheter and transition to a hemodialysis until the infection has healed.

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