金属氧化物铁氧体在磁热效应过程中的作用 - 综述。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Santhiya R, A. Ruban Kumar
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引用次数: 0

摘要

人们对纳米铁氧体的制造进行了广泛的研究,其在磁热疗中的应用已在癌症治疗中显示出良好的效果。本研究的主要目的是概述合成磁性纳米粒子(MNPs)用于热疗的最新进展。磁性纳米粒子具有生物相容性和稳定的磁性状态,纳米铁氧体已被公认为生物医学应用中的顶级热源,特别是用于治疗磁性热疗。利用掺杂剂材料、生物相容性覆盖层和制备技术,可以研究纳米铁氧体的有效性。此外,将纳米铁氧体用于癌症治疗(如磁热疗法)需要满足特定的要求。这些要求包括低毒性、生物相容性、更高的特定吸收率、更短的达到目标热疗温度的时间、生物半径内的结晶尺寸以及更低的纳米铁氧体剂量。潜在的解决方案包括找出限制因素,并提出增强型纳米复合材料,通过生物相容性覆盖层放大其磁性特征,同时优化磁性纳米铁氧体的功效和功能。为了提高铁氧体纳米粒子在治疗热疗中的有效性,本研究将找出它们的局限性,并为更有效的基于铁氧体的纳米复合材料提供解决方案,这可能被证明是未来治疗癌症的一种可行选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of metal oxide ferrites in the process of magnetic hyperthermia – A review
Extensive research has been conducted on the manufacturing of nano ferrites, and their use in magnetic hyperthermia therapy has shown promising results in cancer treatment. This study aims primarily to provide an overview of the latest developments in the synthesis of magnetic nanoparticles (MNPs) for the treatment of hyperthermia. Magnetic nanoparticles are biocompatible and have a stable magnetic state, nano ferrites have become recognized as apex thermoseeds in biomedical applications, specifically for the treatment of magnetic hyperthermia. Employing dopant materials, biocompatible overlay, and preparation techniques, one may study the effectiveness of nano ferrites. Furthermore, specific requirements need to be met for using nano ferrites in cancer treatments like magnetic hyperthermia. These include low toxicity, biocompatibility, a higher specific absorption rate, a shorter time to reach the targeted hyperthermia temperature, crystalline size within the biological radius, and a lower dose of the nano ferrite. A potential resolution involves identifying the limitations and proposing enhanced nanocomposite materials that amplify their magnetic characteristics via a biocompatible overlay, all while optimizing the effectiveness and functioning of magnetic nanoferrites. To increase the effectiveness of ferrite nanoparticles in treating hyperthermia, this study will figure out their constraints and offer solutions for more effective ferrite-based nanocomposites that may prove to be a viable therapy option for cancer in the future.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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