胆囊癌神经内分泌肿瘤成分的肝复发

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-21 DOI:10.1097/RLU.0000000000005539

Tatsuki Ikejiri, Tomoaki Yoh, Yosuke Kasai, Kazuyuki Nagai, Etsuro Hatano

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引用次数: 0

摘要

摘要：一名60岁的男性因患T2N0M0胆囊癌（GBC）接受了扩大胆囊切除术和区域淋巴结切除术，术后显示出明显的FDG摄取（SUVmax = 6.5）。然而，术后24个月的CT扫描发现了多个肝包块。与原发性 GBC 不同的是，肝肿块显示出有限的 FDG 摄取（SUVmax = 3.7）。肿瘤活检显示诊断为 3 级神经内分泌肿瘤。此外，肝脏肿块在体生长抑素受体闪烁成像中显示出明显的摄取。重新评估后发现，原发切除标本中约有 10% 的神经内分泌肿瘤成分。该病例表明，原发癌和转移癌的 FDG 摄取不同，可能需要进行鉴别诊断。

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Hepatic Recurrence of Neuroendocrine Tumor Component in Gallbladder Cancer.

Abstract: A 60-year-old man underwent an extended cholecystectomy with regional lymphadenectomy for T2N0M0 gallbladder cancer (GBC), which showed significant FDG uptake (SUV max = 6.5). However, CT scan at 24 months postsurgery revealed multiple hepatic masses. Unlike the primary GBC, the hepatic masses showed limited FDG uptake (SUV max = 3.7). A tumor biopsy revealed the diagnosis of a grade 3 neuroendocrine tumor. Furthermore, the hepatic masses showed significant uptake on somatostatin receptor scintigraphy. Upon reevaluation, the primary resected specimen was found to include approximately 10% of neuroendocrine tumor components. This case suggests that different FDG uptake between primary and metastatic cancer may necessitate differential diagnosis.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.