Sandro Giannini, Annalisa Pitino, Stefania Sella, Maria Fusaro, Gaetano Paride Arcidiacono, Marco Onofrio Torres, Martina Zaninotto, Mercedes Gori, Andrea Aghi, Colin Gerard Egan, Paolo Simioni, Giovanni Tripepi, Mario Plebani
{"title":"意大利威尼托大区维生素 D 检测中的性别差异：2005 年至 2016 年的回顾性分析。","authors":"Sandro Giannini, Annalisa Pitino, Stefania Sella, Maria Fusaro, Gaetano Paride Arcidiacono, Marco Onofrio Torres, Martina Zaninotto, Mercedes Gori, Andrea Aghi, Colin Gerard Egan, Paolo Simioni, Giovanni Tripepi, Mario Plebani","doi":"10.1007/s11657-024-01460-w","DOIUrl":null,"url":null,"abstract":"<div><h3>\n <i>Summary</i>\n </h3><p>A retrospective analysis was performed to evaluate the frequency of vitamin D blood testing in individuals from the Padua province, Veneto, Italy from 2005 to 2016. A significant increase in the frequency of vitamin D blood tests, particularly in females was observed and in individuals with severe vitamin D deficiency (Class I).</p><h3>Purpose</h3><p>Vitamin D deficiency has been linked to negative health outcomes that extend beyond bone-related conditions. The frequency of vitamin D blood testing in residents from the Padua province, (Veneto, Italy) from 2005 to 2016 was evaluated.</p><h3>Methods</h3><p>Data were retrospectively retrieved from blood test databases (Laboratory Medicine Unit, Padua University Hospital) and information on number of vitamin D blood tests performed on residents from 2005 to 2016 was collected. Data were stratified by sex and ten birth cohorts from 1901 to 2016. Blood tests were classified into five vitamin D classes: I < 50 nmol/L, II 50–74.9 nmol/L, III 75–149 nmol/L, IV 150–250 nmol/L, and V > 250–1000 nmol/L. Blood test trends were analyzed as blood test rate and vitamin D class rate/resident population. Population analysis was analyzed by incidence rates and stratified by vitamin D class.</p><h3>Results</h3><p>293,013 vitamin D blood tests were conducted between 2005 and 2016 across 10 birth cohorts. Females accounted for 75% of tests and fewer were conducted in the youngest and oldest birth cohorts. Sex differences in vitamin D blood test frequency were observed; adjusted rates ranging from 1.7 to 35.6% for males and 8 to 81% for females from 2005 to 2016. Crude incidence rates (per 1000 from 2005 to 2016) varied from 1.5 to 10.8‰ for males and 7 to 19.4‰ for females. Crude blood test rates for vitamin D deficiency (Class I) increased from 1.1 to 9.9‰ in 2016 for males and 5 to 17.3‰ for females. Crude incidence rates (from 2005 to 2016) for Class I were 9.7–57.1‰ in males and 43.6–92.4‰ in females.</p><h3>Conclusions</h3><p>These findings highlight sex-related differences in vitamin D testing, providing valuable insight for healthcare planning.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"19 1","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11657-024-01460-w.pdf","citationCount":"0","resultStr":"{\"title\":\"Sex-related differences in vitamin D testing in the Veneto Region, Italy: a retrospective analysis from 2005 to 2016\",\"authors\":\"Sandro Giannini, Annalisa Pitino, Stefania Sella, Maria Fusaro, Gaetano Paride Arcidiacono, Marco Onofrio Torres, Martina Zaninotto, Mercedes Gori, Andrea Aghi, Colin Gerard Egan, Paolo Simioni, Giovanni Tripepi, Mario Plebani\",\"doi\":\"10.1007/s11657-024-01460-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>\\n <i>Summary</i>\\n </h3><p>A retrospective analysis was performed to evaluate the frequency of vitamin D blood testing in individuals from the Padua province, Veneto, Italy from 2005 to 2016. A significant increase in the frequency of vitamin D blood tests, particularly in females was observed and in individuals with severe vitamin D deficiency (Class I).</p><h3>Purpose</h3><p>Vitamin D deficiency has been linked to negative health outcomes that extend beyond bone-related conditions. The frequency of vitamin D blood testing in residents from the Padua province, (Veneto, Italy) from 2005 to 2016 was evaluated.</p><h3>Methods</h3><p>Data were retrospectively retrieved from blood test databases (Laboratory Medicine Unit, Padua University Hospital) and information on number of vitamin D blood tests performed on residents from 2005 to 2016 was collected. Data were stratified by sex and ten birth cohorts from 1901 to 2016. Blood tests were classified into five vitamin D classes: I < 50 nmol/L, II 50–74.9 nmol/L, III 75–149 nmol/L, IV 150–250 nmol/L, and V > 250–1000 nmol/L. Blood test trends were analyzed as blood test rate and vitamin D class rate/resident population. Population analysis was analyzed by incidence rates and stratified by vitamin D class.</p><h3>Results</h3><p>293,013 vitamin D blood tests were conducted between 2005 and 2016 across 10 birth cohorts. Females accounted for 75% of tests and fewer were conducted in the youngest and oldest birth cohorts. Sex differences in vitamin D blood test frequency were observed; adjusted rates ranging from 1.7 to 35.6% for males and 8 to 81% for females from 2005 to 2016. Crude incidence rates (per 1000 from 2005 to 2016) varied from 1.5 to 10.8‰ for males and 7 to 19.4‰ for females. Crude blood test rates for vitamin D deficiency (Class I) increased from 1.1 to 9.9‰ in 2016 for males and 5 to 17.3‰ for females. 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引用次数: 0
摘要
研究人员进行了一项回顾性分析，以评估2005年至2016年意大利威尼托大区帕多瓦省居民进行维生素D血液检测的频率。结果发现，维生素 D 血液检测频率明显增加，尤其是女性和严重维生素 D 缺乏症（I 级）患者。我们对 2005 年至 2016 年帕多瓦省（意大利威尼托）居民进行维生素 D 血液检测的频率进行了评估：方法：从血液检测数据库（帕多瓦大学医院实验室医学科）中回顾性检索数据，收集2005年至2016年居民进行维生素D血液检测次数的信息。数据按性别和 1901 年至 2016 年的十个出生队列进行了分层。血液检测结果分为五个维生素 D 等级：I 250-1000 nmol/L。血液检测趋势按血液检测率和维生素 D 等级率/常住人口进行分析。结果：2005 年至 2016 年期间，10 个出生队列共进行了 293 013 次维生素 D 血液检测。其中女性占 75%，在最年轻和最年长的出生队列中进行的检测次数较少。在维生素 D 血液检测频率方面观察到了性别差异；2005 年至 2016 年间，男性的调整率为 1.7% 至 35.6%，女性为 8% 至 81%。粗发病率（2005 年至 2016 年每 1000 人）男性为 1.5 至 10.8‰，女性为 7 至 19.4‰。维生素 D 缺乏症（I 级）的血液检测粗发病率在 2016 年男性从 1.1‰增至 9.9‰，女性从 5‰增至 17.3‰。I级粗发病率（2005年至2016年）男性为9.7-57.1‰，女性为43.6-92.4‰：这些发现凸显了维生素 D 检测中与性别相关的差异，为医疗保健规划提供了宝贵的见解。
Sex-related differences in vitamin D testing in the Veneto Region, Italy: a retrospective analysis from 2005 to 2016
Summary
A retrospective analysis was performed to evaluate the frequency of vitamin D blood testing in individuals from the Padua province, Veneto, Italy from 2005 to 2016. A significant increase in the frequency of vitamin D blood tests, particularly in females was observed and in individuals with severe vitamin D deficiency (Class I).
Purpose
Vitamin D deficiency has been linked to negative health outcomes that extend beyond bone-related conditions. The frequency of vitamin D blood testing in residents from the Padua province, (Veneto, Italy) from 2005 to 2016 was evaluated.
Methods
Data were retrospectively retrieved from blood test databases (Laboratory Medicine Unit, Padua University Hospital) and information on number of vitamin D blood tests performed on residents from 2005 to 2016 was collected. Data were stratified by sex and ten birth cohorts from 1901 to 2016. Blood tests were classified into five vitamin D classes: I < 50 nmol/L, II 50–74.9 nmol/L, III 75–149 nmol/L, IV 150–250 nmol/L, and V > 250–1000 nmol/L. Blood test trends were analyzed as blood test rate and vitamin D class rate/resident population. Population analysis was analyzed by incidence rates and stratified by vitamin D class.
Results
293,013 vitamin D blood tests were conducted between 2005 and 2016 across 10 birth cohorts. Females accounted for 75% of tests and fewer were conducted in the youngest and oldest birth cohorts. Sex differences in vitamin D blood test frequency were observed; adjusted rates ranging from 1.7 to 35.6% for males and 8 to 81% for females from 2005 to 2016. Crude incidence rates (per 1000 from 2005 to 2016) varied from 1.5 to 10.8‰ for males and 7 to 19.4‰ for females. Crude blood test rates for vitamin D deficiency (Class I) increased from 1.1 to 9.9‰ in 2016 for males and 5 to 17.3‰ for females. Crude incidence rates (from 2005 to 2016) for Class I were 9.7–57.1‰ in males and 43.6–92.4‰ in females.
Conclusions
These findings highlight sex-related differences in vitamin D testing, providing valuable insight for healthcare planning.
期刊介绍：
Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
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