Faryal Afridi , Tooba Fida , Muhammad Usama Bin Shabbir , Hasban Ahmad Halim , Ishwa Ghouri , Muhammad Fawad Ashraf
{"title":"埃文斯综合征:一名年轻成人的罕见血液学难题:病例报告","authors":"Faryal Afridi , Tooba Fida , Muhammad Usama Bin Shabbir , Hasban Ahmad Halim , Ishwa Ghouri , Muhammad Fawad Ashraf","doi":"10.1016/j.hmedic.2024.100121","DOIUrl":null,"url":null,"abstract":"<div><div>Evans syndrome is a rare autoimmune-mediated cytopenic disorder. We described the case of a male 27-year-old who had a 15-day history of fever, cough, and myalgia. Although the clinical examination other than a fever is unremarkable, blood workup and cytochemistry showed an autoimmune hemolytic reaction and peripheral destruction of platelets consistent with Evans syndrome. The patient was given multiple transfusions of RBC and platelets in addition to oral corticosteroids, parenteral folic acid, and vitamin B12. This case highlights the importance of considering Evans Syndrome in the differential diagnosis and timely management for a better patient outcome. The following prescriptions were given to the patient upon discharge: injectable deltacortil, tab folic acid, and Cap Opt-D. The patient was instructed to come see the outpatient department at the hospital. This case report highlights the uncharted region of Evans Syndrome in Pakistan.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"8 ","pages":"Article 100121"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evans syndrome: An uncommon hematological conundrum in a young adult: A case report\",\"authors\":\"Faryal Afridi , Tooba Fida , Muhammad Usama Bin Shabbir , Hasban Ahmad Halim , Ishwa Ghouri , Muhammad Fawad Ashraf\",\"doi\":\"10.1016/j.hmedic.2024.100121\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Evans syndrome is a rare autoimmune-mediated cytopenic disorder. We described the case of a male 27-year-old who had a 15-day history of fever, cough, and myalgia. Although the clinical examination other than a fever is unremarkable, blood workup and cytochemistry showed an autoimmune hemolytic reaction and peripheral destruction of platelets consistent with Evans syndrome. The patient was given multiple transfusions of RBC and platelets in addition to oral corticosteroids, parenteral folic acid, and vitamin B12. This case highlights the importance of considering Evans Syndrome in the differential diagnosis and timely management for a better patient outcome. The following prescriptions were given to the patient upon discharge: injectable deltacortil, tab folic acid, and Cap Opt-D. The patient was instructed to come see the outpatient department at the hospital. This case report highlights the uncharted region of Evans Syndrome in Pakistan.</div></div>\",\"PeriodicalId\":100908,\"journal\":{\"name\":\"Medical Reports\",\"volume\":\"8 \",\"pages\":\"Article 100121\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S294991862400086X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S294991862400086X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
埃文斯综合征是一种罕见的自身免疫介导的细胞减少性疾病。我们描述了一例 27 岁男性患者的病例,他有 15 天的发热、咳嗽和肌痛病史。虽然除发热外,其他临床检查均无异常,但血液检查和细胞化学检查显示,其自身免疫性溶血反应和外周血小板破坏与埃文斯综合征一致。除了口服皮质类固醇、肠外叶酸和维生素 B12 外,患者还多次输注红细胞和血小板。本病例强调了在鉴别诊断中考虑埃文斯综合征的重要性,及时治疗可使患者获得更好的预后。患者出院时获得了以下处方:注射用溴氢可的松、叶酸片和 Cap Opt-D。并嘱咐患者到医院门诊部就诊。本病例报告突显了埃文斯综合征在巴基斯坦的未知领域。
Evans syndrome: An uncommon hematological conundrum in a young adult: A case report
Evans syndrome is a rare autoimmune-mediated cytopenic disorder. We described the case of a male 27-year-old who had a 15-day history of fever, cough, and myalgia. Although the clinical examination other than a fever is unremarkable, blood workup and cytochemistry showed an autoimmune hemolytic reaction and peripheral destruction of platelets consistent with Evans syndrome. The patient was given multiple transfusions of RBC and platelets in addition to oral corticosteroids, parenteral folic acid, and vitamin B12. This case highlights the importance of considering Evans Syndrome in the differential diagnosis and timely management for a better patient outcome. The following prescriptions were given to the patient upon discharge: injectable deltacortil, tab folic acid, and Cap Opt-D. The patient was instructed to come see the outpatient department at the hospital. This case report highlights the uncharted region of Evans Syndrome in Pakistan.