原发性中枢神经系统血管炎--治疗重点综述。

IF 2.6 Q2 PERIPHERAL VASCULAR DISEASE

Vascular Health and Risk Management Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI:10.2147/VHRM.S488202

Praveen Kesav, Divya Manesh Raj, Rula A Hajj-Ali, Syed I Hussain, Seby John

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引用次数: 0

摘要

原发性中枢神经系统血管炎（PCNSV）是一种罕见而复杂的疾病，给诊断和治疗带来了巨大挑战。自 20 世纪 50 年代被确认为一种独特的临床实体以来，我们对 PCNSV 组织病理学、特定临床亚群及其对治疗的反应的认识有了长足的进步。然而，PCNSV 是最罕见的血管炎之一，其诊断仍然具有挑战性，在最佳治疗方面仍有许多未解之谜。在本综述中，我们将详细介绍目前治疗 PCNSV 的方法。我们详尽回顾了现有的 PCNSV 队列研究，并对研究定义、治疗方法和治疗结果预测因素等数据进行了批判性评估。最后，我们还提出了 PCNSV 的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Primary CNS Vasculitis - A Focussed Review on Treatment.

Primary central nervous system vasculitis (PCNSV) is a rare and complex disease that poses formidable diagnostic and therapeutic challenges. Since its initial recognition as a distinct clinical entity in the 1950s, there has been considerable advancement in our understanding of PCNSV histopathology, specific clinical subsets, and their response to treatment. However, PCNSV is one of the rarest vasculitides, and still remains a challenging diagnosis with many unanswered questions regarding optimal management. In this review, we intend to provide a detailed outline of approaches that are currently being employed for the treatment of PCNSV. We exhaustively review available cohort series of PCNSV and critically appraise the data for study definitions, treatment approaches, and predictors of treatment outcomes. Finally, we also propose a treatment approach for PCNSV.

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来源期刊

Vascular Health and Risk Management PERIPHERAL VASCULAR DISEASE-

CiteScore

4.20

自引率

3.40%

发文量

109

审稿时长

16 weeks

期刊介绍： An international, peer-reviewed journal of therapeutics and risk management, focusing on concise rapid reporting of clinical studies on the processes involved in the maintenance of vascular health; the monitoring, prevention, and treatment of vascular disease and its sequelae; and the involvement of metabolic disorders, particularly diabetes. In addition, the journal will also seek to define drug usage in terms of ultimate uptake and acceptance by the patient and healthcare professional.