首次报告阿尔及利亚的非洲金狼(Canis lupaster)体内发现 Angiostrongylus vasorum。

IF 3 2区 医学 Q1 PARASITOLOGY
Noureddine Mechouck, Georgiana Deak, Angela Monica Ionică, Corina Toma, Andrada Gabriela Negoescu, Marian Taulescu, Zihad Bouslama, Andrei Daniel Mihalca
{"title":"首次报告阿尔及利亚的非洲金狼(Canis lupaster)体内发现 Angiostrongylus vasorum。","authors":"Noureddine Mechouck, Georgiana Deak, Angela Monica Ionică, Corina Toma, Andrada Gabriela Negoescu, Marian Taulescu, Zihad Bouslama, Andrei Daniel Mihalca","doi":"10.1186/s13071-024-06534-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Angiostrongylus vasorum, commonly known as the \"French heartworm,\" is a nematode belonging to the Metastrongyloidea superfamily. This parasite was first identified in Toulouse, France in 1853 infecting the pulmonary arteries and the right side of the heart of a Pointer dog. Angiostrongylosis is an important infection due its severe clinical signs and potential for causing high morbidity and mortality in domestic dogs. This nematode has not been studied in Algeria. The aim of this study was investigate the presence of lungworms among different mammal species in a number of Algerian regions.</p><p><strong>Methods: </strong>Between February 2022 and September 2023, 47 road-killed animals were collected from six administrative units (departments) in Algeria. All carcasses underwent a full parasitological necropsy, and lung tissues were preserved in 10% buffered formalin and concentrated ethanol for further study. All collected samples were subjected to histological and PCR (cytochrome c oxidase subunit 1 gene) analyses for lungworm identification.</p><p><strong>Results: </strong>Histological examination revealed the presence of nematode eggs and larvae in the alveolar space and chronic obstructive vascular changes were detected in a single golden African wolf (Canis lupaster) collected from the department of Constantine. First-stage larvae were collected and morphologically identified as Angiostrongylus spp. The molecular identification confirmed the presence of A. vasorum. All other animals tested were negative for lungworms.</p><p><strong>Conclusions: </strong>To the best of our knowledge, this is the first report of A. vasorum infection in an African golden wolf (Canis lupaster). We report a new host association, highlighting the importance of further studies to update the geographical distribution of A. vasorum and its epidemiology across Algeria.</p>","PeriodicalId":19793,"journal":{"name":"Parasites & Vectors","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520683/pdf/","citationCount":"0","resultStr":"{\"title\":\"First report of Angiostrongylus vasorum in an African golden wolf (Canis lupaster) in Algeria.\",\"authors\":\"Noureddine Mechouck, Georgiana Deak, Angela Monica Ionică, Corina Toma, Andrada Gabriela Negoescu, Marian Taulescu, Zihad Bouslama, Andrei Daniel Mihalca\",\"doi\":\"10.1186/s13071-024-06534-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Angiostrongylus vasorum, commonly known as the \\\"French heartworm,\\\" is a nematode belonging to the Metastrongyloidea superfamily. This parasite was first identified in Toulouse, France in 1853 infecting the pulmonary arteries and the right side of the heart of a Pointer dog. Angiostrongylosis is an important infection due its severe clinical signs and potential for causing high morbidity and mortality in domestic dogs. This nematode has not been studied in Algeria. The aim of this study was investigate the presence of lungworms among different mammal species in a number of Algerian regions.</p><p><strong>Methods: </strong>Between February 2022 and September 2023, 47 road-killed animals were collected from six administrative units (departments) in Algeria. All carcasses underwent a full parasitological necropsy, and lung tissues were preserved in 10% buffered formalin and concentrated ethanol for further study. All collected samples were subjected to histological and PCR (cytochrome c oxidase subunit 1 gene) analyses for lungworm identification.</p><p><strong>Results: </strong>Histological examination revealed the presence of nematode eggs and larvae in the alveolar space and chronic obstructive vascular changes were detected in a single golden African wolf (Canis lupaster) collected from the department of Constantine. First-stage larvae were collected and morphologically identified as Angiostrongylus spp. The molecular identification confirmed the presence of A. vasorum. All other animals tested were negative for lungworms.</p><p><strong>Conclusions: </strong>To the best of our knowledge, this is the first report of A. vasorum infection in an African golden wolf (Canis lupaster). We report a new host association, highlighting the importance of further studies to update the geographical distribution of A. vasorum and its epidemiology across Algeria.</p>\",\"PeriodicalId\":19793,\"journal\":{\"name\":\"Parasites & Vectors\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-10-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520683/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Parasites & Vectors\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s13071-024-06534-9\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PARASITOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Parasites & Vectors","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13071-024-06534-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PARASITOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景:Angiostrongylus vasorum俗称 "法国心丝虫",是一种线虫,属于Metastrongyloidea超科。这种寄生虫于 1853 年在法国图卢兹首次被发现,当时感染了一只波因特犬的肺动脉和右侧心脏。血管软骨虫病是一种重要的传染病,因为它有严重的临床症状,并可能导致家犬的高发病率和高死亡率。阿尔及利亚尚未对这种线虫进行过研究。本研究的目的是调查阿尔及利亚多个地区不同哺乳动物物种中是否存在肺线虫:方法:2022 年 2 月至 2023 年 9 月期间,从阿尔及利亚的六个行政单位(省)收集了 47 只在公路上被杀死的动物。对所有尸体进行了全面的寄生虫尸体解剖,并将肺组织保存在 10%缓冲福尔马林和浓乙醇中,以备进一步研究。对所有采集的样本进行组织学和 PCR(细胞色素 c 氧化酶亚基 1 基因)分析,以鉴定肺线虫:结果:组织学检查显示,在君士坦丁省采集的一只金毛非洲狼(Canis lupaster)的肺泡间隙中存在线虫卵和幼虫,并检测到慢性阻塞性血管变化。收集到的第一期幼虫经形态学鉴定为 Angiostrongylus spp。 分子鉴定证实了 A. vasorum 的存在。所有其他接受检测的动物对肺蠕虫均呈阴性:据我们所知,这是非洲金狼(Canis lupaster)感染A. vasorum的首次报道。我们报告了一种新的宿主关联,强调了进一步研究以更新A. vasorum在阿尔及利亚的地理分布及其流行病学的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
First report of Angiostrongylus vasorum in an African golden wolf (Canis lupaster) in Algeria.

Background: Angiostrongylus vasorum, commonly known as the "French heartworm," is a nematode belonging to the Metastrongyloidea superfamily. This parasite was first identified in Toulouse, France in 1853 infecting the pulmonary arteries and the right side of the heart of a Pointer dog. Angiostrongylosis is an important infection due its severe clinical signs and potential for causing high morbidity and mortality in domestic dogs. This nematode has not been studied in Algeria. The aim of this study was investigate the presence of lungworms among different mammal species in a number of Algerian regions.

Methods: Between February 2022 and September 2023, 47 road-killed animals were collected from six administrative units (departments) in Algeria. All carcasses underwent a full parasitological necropsy, and lung tissues were preserved in 10% buffered formalin and concentrated ethanol for further study. All collected samples were subjected to histological and PCR (cytochrome c oxidase subunit 1 gene) analyses for lungworm identification.

Results: Histological examination revealed the presence of nematode eggs and larvae in the alveolar space and chronic obstructive vascular changes were detected in a single golden African wolf (Canis lupaster) collected from the department of Constantine. First-stage larvae were collected and morphologically identified as Angiostrongylus spp. The molecular identification confirmed the presence of A. vasorum. All other animals tested were negative for lungworms.

Conclusions: To the best of our knowledge, this is the first report of A. vasorum infection in an African golden wolf (Canis lupaster). We report a new host association, highlighting the importance of further studies to update the geographical distribution of A. vasorum and its epidemiology across Algeria.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Parasites & Vectors
Parasites & Vectors 医学-寄生虫学
CiteScore
6.30
自引率
9.40%
发文量
433
审稿时长
1.4 months
期刊介绍: Parasites & Vectors is an open access, peer-reviewed online journal dealing with the biology of parasites, parasitic diseases, intermediate hosts, vectors and vector-borne pathogens. Manuscripts published in this journal will be available to all worldwide, with no barriers to access, immediately following acceptance. However, authors retain the copyright of their material and may use it, or distribute it, as they wish. Manuscripts on all aspects of the basic and applied biology of parasites, intermediate hosts, vectors and vector-borne pathogens will be considered. In addition to the traditional and well-established areas of science in these fields, we also aim to provide a vehicle for publication of the rapidly developing resources and technology in parasite, intermediate host and vector genomics and their impacts on biological research. We are able to publish large datasets and extensive results, frequently associated with genomic and post-genomic technologies, which are not readily accommodated in traditional journals. Manuscripts addressing broader issues, for example economics, social sciences and global climate change in relation to parasites, vectors and disease control, are also welcomed.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信