在摩洛哥一家医院手术的社区腹膜炎细菌学概况。

Access microbiology Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI:10.1099/acmi.0.000816.v5
Samia Bazhar, Elmostafa Benaissa, Fatima Ziad, Leila Laamara, Yassine Ben Lahlou, Mariama Chadli, Mostafa Elouennass
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引用次数: 0

摘要

简介腹膜炎的特点是腹膜急性发炎,通常由消化器官穿孔或腹腔内化脓性病灶引起。腹膜炎可由感染或非感染引起。涉及的细菌是消化道菌群(肠杆菌科和厌氧菌)中的细菌,而革兰阳性球菌和酵母菌则可能在医院感染中分离出来。我们的研究旨在分离和鉴定社区获得性腹膜炎的病菌,以评估它们对我国现有抗生素的敏感性。研究方法。这是一项关于摩洛哥拉巴特社区腹膜炎细菌学概况的回顾性研究。在2022年7月1日至2023年4月30日期间,共收治了150名成年腹膜炎患者,并在术中采集样本进行细菌学检查。结果150 名患者中,101 名(67.8%)为男性,49 名(32.2%)为女性,男女性别比为 2 :1.患者的平均年龄为(40.5±20.12)岁。细菌分布以大肠杆菌为主(44%)。总体而言,70%的大肠埃希菌对氨苄西林具有耐药性,而肠球菌对氨苄西林没有耐药性。讨论。在本研究中,我们对社区腹膜炎的细菌学概况很感兴趣,以便根据细菌生态学调整抗生素疗法。我们的研究结果表明,在我们的临床环境中,大肠杆菌对常用的阿莫西林/克拉维酸复方制剂的耐药性呈上升趋势。结论是因此,有必要重新评估治疗社区获得性腹膜炎的经验性抗生素处方。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bacteriological profile of community peritonitis operated in a Moroccan Hospital.

Introduction. Peritonitis is characterized by acute inflammation of the peritoneum, often resulting from digestive organ perforation or intra-abdominal septic focus. It may be of either infectious or non-infectious origin. The bacteria involved are those of the digestive flora (Enterobacteriaceae and anaerobes), while Gram-positive cocci and yeasts can be isolated in nosocomial infections. Our study aims to isolate and identify the germs involved in community-acquired peritonitis in order to assess their susceptibility to the antibiotics available in our country. Methods. This is a retrospective study of the bacteriological profile of community peritonitis in Rabat Morocco. A total of 150 adult patients with peritonitis were admitted and samples were collected intraoperatively for bacteriological examination between 1 July 2022 and 30 April 2023. Results. Among the 150 patients, 101 (67.8%) were males and 49 (32.2%) were females, with a sex ratio (M/F) of 2 : 1. The mean age of the patients was 40.5 years±20.12. The distribution of bacteria was dominated by Escherichia coli (44%). Overall, 70% of E. coli isolated exhibited resistance to ampicillin, whereas no resistance to ampicillin has been reported for Enterococcus. Discussion. In the present study, we were interested in the bacteriological profile of community peritonitis in order to adapt the antibiotic therapy to our bacterial ecology. Our findings indicate a concerning trend of increasing resistance among E. coli to the commonly used amoxicillin/clavulanic acid combination in our clinical setting. Conclusion. Consequently, there is a need to reassess the empiric antibiotic prescribed for the management of community-acquired peritonitis.

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