拉美国家单个中心的失代偿性心力衰竭:ICARUS 登记册首批 1595 例病例的研究结果。

Lyda Z Rojas, Sergio A Gómez-Ochoa, Jaime A Rodríguez, Karen A García-Rueda, Angela M Torres-Bustamante, Daniel R Botero, María Cantillo-Reines, Angie Y Serrano-García, Adriana M Jurado, Kelly J Castro, Katerine Pinilla, Angie C Mendoza-Quiñonez, Nelly J Vasquez, Yeinmy Y Alvarez, Maribel Rojas, Diana M Ortega-Solano, Yesenia Sanabria, Angelica Vargas-Sanabria, Aura M Cáceres, Paula S Bohorquez-Hernández, Carlos Portillo, Luis E Echeverría
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引用次数: 0

摘要

摘要描述急性失代偿性心力衰竭(ADHF)住院患者的方法、社会人口学和临床特征及其短期疗效:方法:对心血管中心急诊科的急性失代偿性心力衰竭患者进行前瞻性队列研究。结果:1595 名 ADHF 患者:1595名 ADHF 患者。中位年龄为 68 岁(Q1 = 58;Q3 = 76),69.28% 为男性。住院时间中位数为 6 天(Q1 = 4;Q3 = 11),30 天后再次住院的累计发生率为 8.70% (95% CI 7.18-10.40%),院内死亡率累计发生率为 4.33% (95% CI 3.38-5.44%),30 天后明尼苏达心衰患者生活质量评分的中位数变化为-20 分(Q1 = -37;Q3 = -5)。出院时,所有患者使用四联神经激素阻断疗法的比例均大于70%:急性失代偿性心力衰竭地区机构(ICARUS)是拉丁美洲最早的研究之一,它证明了描述急性失代偿性心力衰竭患者特征的重要性,而对心力衰竭指南的遵守可能对良好的临床结果产生了影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Decompensated heart failure in a single center of a Latin American country: findings from the first 1595 cases in the ICARUS registry.

Objective: Describe the methodological aspects, sociodemographic, and clinical characteristics of patients hospitalized with acute decompensated heart failure (ADHF) and their short-term outcomes.

Methods: Prospective cohort of patients with ADHF from the emergency service of the cardiovascular center. Descriptive statistics were used to synthesize sociodemographic characteristics, clinical characteristics during hospitalization, and outcomes.

Results: 1595 patients with ADHF. The median age was 68 years (Q1 = 58; Q3 = 76), and 69.28% were men. The median hospital stay was 6 days (Q1 = 4; Q3 = 11), with an cumulative incidence for re-hospitalization at 30 days of 8.70% (95% CI 7.18-10.40%), in-hospital mortality cumulative incidence of 4.33% (95% CI 3.38-5.44%), and a median change in the quality-of-life score Minnesota Living with Heart Failure at 30 days of -20 points (Q1 = -37; Q3 = -5). At discharge, all patients had a percentage > 70% of the use of quadruple neurohormonal blockade therapy.

Conclusion: Institutional aCute decompensAted HeaRt FailUre RegiStry (ICARUS) is one of the first studies in Latin America to demonstrate the importance of characterizing the population with ADHF and the adherence to heart failure guidelines may have influenced the favorable clinical outcomes.

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