心血管疾病中的微塑料和纳米塑料--一篇令人担忧的联系的叙述性综述。

IF 3.6 Q2 TOXICOLOGY
Frontiers in toxicology Pub Date : 2024-10-10 eCollection Date: 2024-01-01 DOI:10.3389/ftox.2024.1479292
Haixiang Zheng, Gianpaolo Vidili, Gavino Casu, Eliano Pio Navarese, Leonardo A Sechi, Youren Chen
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引用次数: 0

摘要

随着塑料产品的广泛使用和废弃物的增加,微塑料和纳米塑料(MNPs)已成为全球环境污染的一个重要问题。近年来,越来越多的研究表明,MNPs 可能会对人类健康产生负面影响。本综述旨在探讨 MNPs 与心血管疾病之间的关联,并对未来研究进行展望。研究表明,接触 MNPs 与心血管疾病之间可能存在联系。实验室研究表明,暴露于 MNPs 的动物通常会表现出心血管系统异常,如血压升高、血管炎症和心肌损伤。流行病学调查也显示,接触过 MNPs 的人更容易罹患高血压和心肌梗塞等心血管疾病。虽然具体的影响机制尚不完全清楚,但有几种可能的作用途径,包括有毒物质对 MNPs 的影响和对内分泌系统的干扰。总之,暴露于 MNPs 可能会对心血管健康产生负面影响,但仍需进一步研究以确认其具体机制和影响程度,从而为相关的公共卫生和环境政策提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microplastics and nanoplastics in cardiovascular disease-a narrative review with worrying links.

With the widespread use of plastic products and the increase in waste, microplastics and nanoplastics (MNPs) have become an important issue in global environmental pollution. In recent years, an increasing number of studies have shown that MNPs may have negative impacts on human health. This review aimed to explore the association between MNPs and cardiovascular disease and provide an outlook for future research. Research has shown that there may be a link between MNPs exposure and cardiovascular disease. Laboratory studies have shown that animals exposed to MNPs often exhibit abnormalities in the cardiovascular system, such as increased blood pressure, vascular inflammation, and myocardial damage. Epidemiological surveys have also revealed that people exposed to MNPs are more likely to suffer from cardiovascular diseases, such as hypertension and myocardial infarction. Although the specific impact mechanism is not fully understood, there are several possible pathways of action, including the effects of toxic substances on MNPs and interference with the endocrine system. In summary, MNPs exposure may have a negative impact on cardiovascular health, but further research is needed to confirm its specific mechanism and extent of impact to guide relevant public health and environmental policies.

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CiteScore
3.80
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