证实对氨基青霉素类药物有迟发性超敏反应的患者对青霉素 V 的耐受性。

IF 8.2 1区医学 Q1 ALLERGY

Journal of Allergy and Clinical Immunology-In Practice Pub Date : 2025-01-01 DOI:10.1016/j.jaip.2024.10.018

Ibtihal Alotaibi MD , Rabea Y. Khoudja MD , Ghislaine A.C. Isabwe MD , Michael Fein MD , Florian Stehlin MD , Fiona James BBiomedSci , Moshe Ben-Shoshan MD, MSc , Jason A. Trubiano MBBS, BBiomedSci, PhD , Ana Maria Copaescu MD

引用次数: 0

摘要

延迟性药物超敏反应具有多种临床表型，从常见的黄斑丘疹性渗漏（MPE）到罕见但严重的药物反应伴嗜酸性粒细胞增多和全身症状（DRESS）很少有研究表明，氨基青霉素和氨基头孢菌素的r1侧链在延迟（t细胞介导的）超敏反应中具有交叉反应性，并对其他青霉素和头孢菌素具有耐受性。2,3我们的目的是描述一组确认对氨基青霉素延迟超敏的患者，他们可以安全耐受青霉素V，因为青霉素V具有不同的R1侧链。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Tolerance of penicillin V in patients with confirmed delayed hypersensitivity reactions to aminopenicillins

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来源期刊

Journal of Allergy and Clinical Immunology-In Practice ALLERGYIMMUNOLOGY-IMMUNOLOGY

CiteScore

11.10

自引率

9.60%

发文量

683

审稿时长

50 days

期刊介绍： JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.