Thomas Butters, Lynsey Williams, Charanjit Kaur, Zoltan Szollosi
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引用次数: 0
摘要
伴有微小浸润的原位小叶癌(LCIS)是一种罕见病变,在文献中鲜有报道。我们描述了一例切除纤维上皮病变后的微小浸润性 LCIS。该病灶在超声波检查和乳腺 X 射线检查中分别被分级为 U3 和 M3,在核心针活检中被描述为具有 "异常特征 "的纤维上皮病变。显微镜检查发现,纤维上皮病变的病灶中存在E-粘连蛋白阴性的LCIS,并伴有多个微浸润性典型小叶癌病灶,CK5和S100染色显示其缺乏肌上皮层。
Microinvasive lobular carcinoma arising in a benign phyllodes tumour - a short report and brief review of the literature.
Lobular carcinoma in situ (LCIS) with microinvasion is a rare entity which is rarely reported in the literature. We describe a case of microinvasive LCIS following excision of a fibroepithelial lesion. The lesion was graded as U3 and M3 on ultrasonography and mammography respectively, and on core needle biopsy was described as a fibroepithelial lesion with 'unusual features'. Microscopic examination revealed a fibroepithelial lesion focally colonised by florid E-cadherin negative LCIS with multiple foci of microinvasive classical lobular carcinoma, which lacked a myoepithelial layer on CK5 and S100 staining.
期刊介绍:
Polish Journal of Pathology is an official magazine of the Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology. For the last 18 years of its presence on the market it has published more than 360 original papers and scientific reports, often quoted in reviewed foreign magazines. A new extended Scientific Board of the quarterly magazine comprises people with recognised achievements in pathomorphology and biology, including molecular biology and cytogenetics, as well as clinical oncology. Polish scientists who are working abroad and are international authorities have also been invited. Apart from presenting scientific reports, the magazine will also play a didactic and training role.