住院儿科患者 COVID-19 的严重程度概况

IF 2 4区 医学 Q2 PEDIATRICS
Vânia Chagas da Costa, Ulisses Ramos Montarroyos, Katiuscia Araújo de Miranda Lopes, Ana Célia Oliveira Dos Santos
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引用次数: 0

摘要

目的我们旨在描述与 COVID-19 住院患儿病情严重程度相关的临床特征:这是一项在两家医院进行的流行病学队列研究,其中一家医院是治疗 COVID-19 病例的参考中心。数据收集自医院流行病学中心生成的报告,以及 2020 年 3 月至 2021 年 6 月期间住院的诊断为 COVID-19 的 0 至 14 岁患者的病历。为了分析临床特征与严重程度之间的关联,病例被分为重度(重度和危重)和非重度(无症状、轻度和中度):结果:在队列随访的 191 名儿童中,73.3% 患有重症。血氧饱和度低于 95% 的儿童占 46.6%。在多变量分析中,估计哮喘未得到控制(RR = 13.2)、超重或肥胖(RR = 3.21)、有咳嗽症状(RR = 2.72)和年龄不足一岁(RR = 3.23)的儿童患严重哮喘的风险较高:这一结果突出表明,在考虑确诊为 COVID-19 的临床特征儿童时,有必要改善各个层面的儿童医疗保健以及哮喘和营养管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Severity Profile of COVID-19 in Hospitalized Pediatric Patients.

Objective: We aimed to describe the clinical characteristics associated with severity in children hospitalized with COVID-19.

Method: This was an epidemiological cohort study conducted in two hospitals, one of which was a reference center for the treatment of COVID-19 cases. Data were collected from the reports generated by the hospital epidemiology centers and the medical records of patients aged between 0 and 14 years with a diagnosis of COVID-19, hospitalized between March 2020 and June 2021. To analyze the association between the clinical profile and severity, the cases were classified as severe (severe and critical) and non-severe (asymptomatic, mild, and moderate).

Results: Of the 191 children followed up in the cohort, 73.3% developed the severe form. The percentage of children with oxygen saturation below 95% was 46.6%. In the multivariate analysis, a higher risk of severity was estimated among children with uncontrolled asthma (RR = 13.2), who were overweight or obese (RR = 3.21), who had cough symptoms (RR = 2.72), and those aged under one year (RR = 3.23).

Conclusions: This result underscores the need to improve healthcare at every level for children and for the management of asthma and nutrition when considering children with this clinical profile who are diagnosed with COVID-19.

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来源期刊
Children-Basel
Children-Basel PEDIATRICS-
CiteScore
2.70
自引率
16.70%
发文量
1735
审稿时长
6 weeks
期刊介绍: Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries. The publication focuses on sharing clinical, epidemiological and translational science relevant to children’s health. Moreover, the primary goals of the publication are to highlight under‑represented pediatric disciplines, to emphasize interdisciplinary research and to disseminate advances in knowledge in global child health. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in pediatric medicine. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.
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