{"title":"[通过免疫基因组学鉴定免疫检查点抑制剂的预测性生物标记物]。","authors":"Taigo Kato","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The research field of immunogenomics, which elucidates the detail information of immune cells and HLA based on genomic information, is becoming an essential field for understanding the pathology not only in cancer field but also in autoimmune diseases, organ transplantation, and other areas where immune responses are involved. With the comprehensive understanding of T cell receptors, B cell receptors, cancer mutational profiling, we believe that immunogenomics will greatly contribute to personalized medicine by elucidating various pathological and immunological conditions. In this article, we introduce specific examples of immunogenomics in cancer field for better understanding Immunogenomics.</p>","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"51 9","pages":"869-872"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Identification of Predictive Biomarkers for Immune Checkpoint Inhibitors by Immunogenomics].\",\"authors\":\"Taigo Kato\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The research field of immunogenomics, which elucidates the detail information of immune cells and HLA based on genomic information, is becoming an essential field for understanding the pathology not only in cancer field but also in autoimmune diseases, organ transplantation, and other areas where immune responses are involved. With the comprehensive understanding of T cell receptors, B cell receptors, cancer mutational profiling, we believe that immunogenomics will greatly contribute to personalized medicine by elucidating various pathological and immunological conditions. In this article, we introduce specific examples of immunogenomics in cancer field for better understanding Immunogenomics.</p>\",\"PeriodicalId\":35588,\"journal\":{\"name\":\"Japanese Journal of Cancer and Chemotherapy\",\"volume\":\"51 9\",\"pages\":\"869-872\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Cancer and Chemotherapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Cancer and Chemotherapy","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
根据基因组信息阐明免疫细胞和 HLA 详细信息的免疫基因组学研究领域,不仅在癌症领域,而且在自身免疫性疾病、器官移植和其他涉及免疫反应的领域,都正在成为了解病理的重要领域。随着对 T 细胞受体、B 细胞受体、癌症突变图谱的全面了解,我们相信免疫基因组学将通过阐明各种病理和免疫状况,为个性化医疗做出巨大贡献。本文将介绍免疫基因组学在癌症领域的具体实例,以便更好地理解免疫基因组学。
[Identification of Predictive Biomarkers for Immune Checkpoint Inhibitors by Immunogenomics].
The research field of immunogenomics, which elucidates the detail information of immune cells and HLA based on genomic information, is becoming an essential field for understanding the pathology not only in cancer field but also in autoimmune diseases, organ transplantation, and other areas where immune responses are involved. With the comprehensive understanding of T cell receptors, B cell receptors, cancer mutational profiling, we believe that immunogenomics will greatly contribute to personalized medicine by elucidating various pathological and immunological conditions. In this article, we introduce specific examples of immunogenomics in cancer field for better understanding Immunogenomics.