谷物产品中的黄曲霉毒素--发生、检测和健康影响概述。

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Mumtahin-ul Kousar , Mifftha Yaseen , Monisa Yousouf , Mudasir Ahmad Malik , Aarizoo Mushtaq , Taha Mukhtar , Rifat Javaid , Anam Aijaz , Abida Jabeen , Tawheed Amin
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引用次数: 0

摘要

黄曲霉毒素是由特定霉菌(即黄曲霉和寄生曲霉)自然产生的毒素。这些毒素存在于各种农产品中,包括玉米、花生、棉籽和坚果等作物。它们有可能在生产、加工和储存的不同阶段污染食品供应。黄曲霉毒素是一种剧毒物质,对人类和动物的健康都有不良影响。检测和监测黄曲霉毒素对确保食品安全至关重要。高效、精确的分析技术,如色谱法和免疫测定法,已被用于精确测量不同物质中的黄曲霉毒素含量。监管机构和世界性协会已经确定了食品和营养品中黄曲霉毒素的最高允许限量,以保护公众的健康。要有效解决黄曲霉毒素污染问题,就必须采取全面的方法,包括农业、收获后做法和监管措施方面的各种战略。为了最大限度地减少黄曲霉毒素的接触并降低相关风险,持续的研究和合作努力至关重要。本综述全面探讨了黄曲霉毒素的存在、对健康的影响以及消除黄曲霉毒素的相关技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Aflatoxins in cereal based products-an overview of occurrence, detection and health implication

Aflatoxins in cereal based products-an overview of occurrence, detection and health implication
Aflatoxins are naturally produced toxins by specific molds, namely Aspergillus flavus and Aspergillus parasiticus. These toxins can be found in various agricultural products, including crops like maize, peanuts, cottonseed, and tree nuts. They have the potential to contaminate the food supply during different stages of production, processing, and storage. Aflatoxin is a very poisonous substance that has been linked to adverse health effects in both humans and animals. It is essential to detect and monitor aflatoxins to ensure the safety of food. Efficient and precise analytical techniques, such as chromatography and immunoassays, have been used to accurately measure the levels of aflatoxins in different substances. Regulatory bodies and worldwide associations have determined maximum permissible limits for aflatoxins in food and nourishment products to protect the well-being of the general public. Effectively addressing aflatoxin contamination necessitates a comprehensive approach that encompasses various strategies in agriculture, post-harvest practices, and regulatory measures. Continuous research and collaborative endeavors are crucial in order to minimize aflatoxin exposure and mitigate the associated risks. This review offers a comprehensive examination of the presence, health consequences, and elimination techniques associated with aflatoxins.
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来源期刊
Toxicon
Toxicon 医学-毒理学
CiteScore
4.80
自引率
10.70%
发文量
358
审稿时长
68 days
期刊介绍: Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.
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