正常脾脏 T1rho 和较为稳定的肝脏 T1rho 与脾脏 T1rho 比值的年龄和性别相关性变化。

IF 1.3 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren Pub Date : 2024-10-22 DOI:10.1055/a-2428-7409

Yì Xiáng J Wáng, Wei-Ling Yu, Min Deng

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引用次数: 0

摘要

我们使用了两种 T1rho 序列，一种基于快速自旋回波序列 (FSE)，另一种基于梯度回波序列 (GRE)。对 52 名健康志愿者（36 名女性，16 名男性）的脾脏和肝脏 FSE T1rho 值进行了测量，对 14 名健康志愿者（6 名女性，8 名男性）的脾脏和肝脏 GRE T1rho 值进行了测量。这一趋势与女性肝脏的 T1rho 值一致，而男性肝脏的 T1rho 值则没有这种趋势。女性的脾脏 T1rho 均高于男性（92.8 vs 77.3 ms），pliver/T1rhospleen 在很大程度上消除了性别和年龄的影响。月经期女性的脾脏 T1rho 比非月经期女性低 10.7%（P=0.012），而月经期女性的肝脏 T1rho 比非月经期女性低 3.8%。由于月经期女性体内铁含量往往较低，因此月经期女性肝脏 T1rho 和脾脏 T1rho 均比非月经期女性短，这说明肝脏和脾脏 T1rho 的生理变化可能并不主要受组织中铁含量的影响。如果病理变化只影响肝脏，而脾脏正常，那么 T1rholiver/T1rhospleen 的比值有可能更好地描述肝脏的病理变化。- 脾脏 T1rho 呈与年龄相关的下降趋势。- 女性的脾脏 T1rho 值高于男性。- 脾脏 T1rho 值约为肝脏 T1rho 值的两倍- 脾脏T1rho与肝脏T1rho呈正相关- Wáng YXJ, Yu W-L, Deng M. 正常脾脏 T1rho 的年龄和性别相关性变化及较稳定的肝脏 T1rho 与脾脏 T1rho 比值Fortschr Röntgenstr 2024; DOI 10.1055/a-2428-7409.

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Age- and sex-related variations of normal spleen T1rho and the more stable liver T1rho to spleen T1rho ratio.

We aim to evaluate the potential age- and sex-related variations of normative values of spleen T1rho.Two T1rho sequences were used, with one based on fast spin echo sequence (FSE) and the other based on gradient echo sequence (GRE). Spleen and liver FSE T1rho values were measured in 52 healthy volunteers (36 females, 16 males), and spleen and liver GRE T1rho values were measured in 14 healthy volunteers (6 females, 8 males).For FSE data, an age-related decreasing trend of spleen T1rho was noted for both females and males. This trend was consistent with female liver T1rho values, while such a trend was not noted for male liver T1rho. Females had a higher T1rho than males, both for the spleen (92.8 vs 77.3 ms, p<0.0001) and for the liver (44.2 vs. 38.9 ms, p<0.0001, FSE data). The spleen T1rho value was approximately double the liver T1rho value. The spleen T1rho and liver T1rho were positively correlated, both for FSE data (r=0.611) and GRE data (r=0.541). When the spleen T1rho was used to normalize the liver T1rho, the ratio of T1rho_liver/T1rho_spleen largely removed the sex and age effect. The spleen T1rho in menstrual phase women was 10.7% lower (p=0.012) than that of non-menstrual phase women, while the liver T1rho in menstrual phase women was 3.8% lower than that of non-menstrual phase women.Since women in the menstrual phase tend to have lower body iron, the fact that both liver T1rho and spleen T1rho are shorter among women in the menstrual phase than women in the non-menstrual phase indicates that liver and spleen T1rho physiological variations may not be dominantly affected by the iron content of the tissue. If a pathology has only affected the liver while the spleen is normal, there is a possibility the ratio T1rho_liver/T1rho_spleen may offer better characterization of liver pathologies. · There is an age-related decreasing trend of spleen T1rho.. · Females have a higher spleen T1rho than males.. · The spleen T1rho value is approximately double the liver T1rho value.. · Spleen T1rho and liver T1rho are positively correlated.. · Wáng YXJ, Yu W-L, Deng M. Age- and sex-related variations of normal spleen T1rho and the more stable liver T1rho to spleen T1rho ratio. Fortschr Röntgenstr 2024; DOI 10.1055/a-2428-7409.

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来源期刊

Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren 医学-核医学

CiteScore

1.20

自引率

5.60%

发文量

340

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