评估丁苯酞和阿托伐他汀联用对急性脑梗死患者神经功能、生活质量和血管内皮功能的影响。

IF 0.7 4区医学 Q4 PHARMACOLOGY & PHARMACY

Pakistan journal of pharmaceutical sciences Pub Date : 2024-09-01

Zhixuan Wu, Maojuan Wang, Quanxi Mao, Ying Li, Zuoxiao Li

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引用次数: 0

摘要

急性脑梗塞对健康构成重大威胁，有效治疗至关重要。这项随机对照试验评估了丁苯酞和阿托伐他汀联合疗法对 124 名急性脑梗塞患者的神经功能、生活质量和血管内皮功能的影响。参与者被随机分为对照组和实验组，后者接受联合疗法。使用 NIHSS、SS-QOL、MBI 和 MoCA 量表以及生化指标进行的客观评估显示，实验组的治疗效果有所改善。这项研究为联合用药治疗急性脑梗塞的临床疗效提供了证据。

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本刊更多论文

Assessment of the impact of combining butylphthalide and atorvastatin on neurological function, quality of life and vascular endothelial function in individuals diagnosed with acute cerebral infarction.

Acute cerebral infarction poses a significant health risk and effective treatment is crucial. This randomized controlled trial assessed the impact of combining Butylphthalide and Atorvastatin on neurological function, quality of life and vascular endothelial function in 124 individuals with acute cerebral infarction. Participants were randomized into control and experimental groups, with the latter receiving the combination therapy. Objective assessments using NIHSS, SS-QOL, MBI and MoCA scales, along with biochemical markers, demonstrated improved outcomes in the experimental group. This study provides evidence for the clinical benefits of the drug combination in managing acute cerebral infarction.

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来源期刊

Pakistan journal of pharmaceutical sciences 医学-药学

CiteScore

1.40

自引率

12.50%

发文量

211

审稿时长

4.5 months

期刊介绍： Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.