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引用次数: 0
摘要
肌肉疏松症是 I. Rosenberg 于 1989 年首次提出的一个概念，自此以后，人们对这一概念进行了广泛的研究，尤其是其与慢性疾病的相关性。近年来，肌肉疏松症与晚期慢性肝病的关系日益密切，导致这些患者的生活质量下降，治疗效果不佳。研究表明，肌肉疏松症在晚期慢性肝病患者中的发病率高达 33%，不仅影响患者的健康，还会导致医疗成本增加。晚期慢性肝病患者体弱的发病率为 27%。鉴于肌肉疏松症和虚弱症在这一人群中的高发病率，早期诊断和治疗对于改善患者的生活质量和减轻全球医疗系统的压力至关重要。
A short history of sarcopenia and frailty and their impact on advanced chronic liver disease.
Sarcopenia, first introduced as a concept by I. Rosenberg in 1989, has since been extensively studied, particularly in its correlation with chronic diseases. In recent years, sarcopenia has been increasingly associated with advanced chronic liver disease, leading to a lower quality of life and poor outcomes for these patients. Studies have shown that sarcopenia has a prevalence of 33% in individuals with advanced chronic liver disease, impacting not only the patient's health but also contributing to increased healthcare costs. The prevalence of frailty in patients with advanced chronic liver disease is 27%. Given the high prevalence of sarcopenia and frailty in this population, early diagnosis and treatment are crucial to improving patient quality of life outcomes and reducing the strain on healthcare systems globally.
期刊介绍：
The Journal of Medicine and Life publishes peer-reviewed articles from various fields of medicine and life sciences, including original research, systematic reviews, special reports, case presentations, major medical breakthroughs and letters to the editor. The Journal focuses on current matters that lie at the intersection of biomedical science and clinical practice and strives to present this information to inform health care delivery and improve patient outcomes. Papers addressing topics such as neuroprotection, neurorehabilitation, neuroplasticity, and neuroregeneration are particularly encouraged, as part of the Journal''s continuous interest in neuroscience research. The Editorial Board of the Journal of Medicine and Life is open to consider manuscripts from all levels of research and areas of biological sciences, including fundamental, experimental or clinical research and matters of public health. As part of our pledge to promote an educational and community-building environment, our issues feature sections designated to informing our readers regarding exciting international congresses, teaching courses and relevant institutional-level events.
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