俄罗斯某城市年轻成年人的主要和残余心脏代谢风险因素。

IF 2.4 3区 医学 Q3 ENVIRONMENTAL SCIENCES
Albina V Sineglazova, Aliya S Fakhrutdinova, Zemfira R Asatullina, Guzel R Mustafina, Taisiya Y Kim, Albina R Nurieva, Swapnil Parve
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引用次数: 0

摘要

背景:心血管疾病是导致全球死亡的主要原因,也是造成暂时性和永久性残疾的重要因素。本研究旨在调查俄罗斯喀山市青壮年样本中原发性和残余性心脏代谢风险因素的负担:这项病例对照研究采用了已在多个国家得到验证的心脏代谢疾病分期(CMDS)分类系统。研究对象包括 191 名年龄在 25-44 岁之间、符合纳入标准但不符合任何排除标准的人。数据收集包括患者卡、面对面患者访谈和体格检查,其中患者卡上的问题来自世界卫生组织的 STEPS 工具。人体测量包括身高、体重和腰围的测量。通过生物电阻抗测量对身体成分进行评估。患者还接受了深入的实验室生化分析:研究对象包括 97 名女性(50.8%)和 94 名男性(49.2%)。参与者的中位年龄为 35.00 岁 [IQR:30.00-39.00]。除了致动脉粥样硬化性血脂和血压升高外,胰岛素水平、胰岛素抵抗、瘦素值和高尿酸血症等其他可诱发残余风险且不属于 CMDS 的风险因素也随着 CMDS 水平的升高而增加:喀山年轻人的心脏代谢风险因素发生率很高。结论:喀山青壮年心血管代谢风险因素的发病率很高,这项研究强调了及早识别和管理青壮年心血管代谢风险因素的必要性,以预防日后心血管疾病的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary and residual cardiometabolic risk factors among young adults in a Russian city.

Background: Cardiovascular diseases are a leading cause of mortality and a significant contributor to temporary and permanent disabilities worldwide. This study aimed to investigate the burden of primary and residual cardiometabolic risk factors in a sample of young adults in the Russian city of Kazan.

Methods: This case-control study used the Cardiometabolic Disease Staging (CMDS) classification system, which has been validated in several countries. The study included 191 individuals aged 25-44 years who met the inclusion criteria but did not meet any exclusion criteria. Data collection involved a patient card with questions from the World Health Organization's STEPS instrument, face-to-face patient interviews, and a physical examination. Anthropometric assessments included height, weight, and waist circumference measurements. Body composition was evaluated using bioelectrical impedance measurements. Patients also underwent in-depth laboratory biochemical analyses.

Results: The study cohort was comprised of 97 females (50.8%) and 94 males (49.2%). The median age of participants was 35.00 years [IQR: 30.00-39.00]. The study cohort showed an increase in all anthropometric parameters, with abdominal obesity and overweight reaching 100% in the CMDS 3. Apart from atherogenic lipids and raised blood pressure, other risk factors that precipitate residual risk and were not part of CMDS, such as insulin levels, insulin resistance, leptin values, and hyperuricemia, increased as CMDS levels increased.

Conclusions: The prevalence of cardiometabolic risk factors was high in young adults in Kazan. This study highlights the need for the early identification and management of cardiometabolic risk factors in young adults to prevent the development of cardiovascular diseases later in life.

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来源期刊
Journal of Health, Population, and Nutrition
Journal of Health, Population, and Nutrition 医学-公共卫生、环境卫生与职业卫生
CiteScore
2.20
自引率
0.00%
发文量
49
审稿时长
6 months
期刊介绍: Journal of Health, Population and Nutrition brings together research on all aspects of issues related to population, nutrition and health. The journal publishes articles across a broad range of topics including global health, maternal and child health, nutrition, common illnesses and determinants of population health.
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