处理复杂的诊断问题:在儿科病例中模拟哮喘加重和感染的过敏性支气管肺曲霉菌病 (ABPA)。

IF 1.1 Q4 PRIMARY HEALTH CARE
Murchana Khound, Bipul K Das, Sreejana Sharma, Jaya S Kaushik
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引用次数: 0

摘要

过敏性支气管肺曲霉菌病(ABPA)与哮喘或感染相似,给儿科诊断带来了困难。一名 11 岁的女孩因哮喘反复住院,出现持续咳嗽和呼吸困难。最初的哮喘治疗暂时缓解了症状,但她对氧气的依赖促使她接受进一步检查。放射学评估初步显示她受到感染,确诊为克雷伯氏肺炎,但抗生素治疗效果不佳。嗜酸性粒细胞、IgE水平和曲霉菌特异性IgE的升高提示她患有ABPA。确诊后,患者成功接受了为期三个月的口服类固醇治疗,并结合多种疗法进行了有效控制。要将 ABPA 与哮喘和感染区分开来,就必须采取彻底的方法,以便及时识别和治疗儿科病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Managing diagnostic complexity: Allergic bronchopulmonary aspergillosis (ABPA) mimicking asthma exacerbation and infections in pediatric cases.

Allergic bronchopulmonary aspergillosis (ABPA) presents diagnostic hurdles in pediatrics due to its resemblance to asthma or infections. An 11-year-old girl, known for recurrent asthma-related hospitalizations, presented with ongoing cough and breathing issues. Initial asthma treatment provided temporary relief, but her reliance on oxygen spurred further investigation. Radiological assessments initially suggested infection, confirmed as Klebsiella pneumonia, but antibiotic treatment proved insufficient. Elevated eosinophils, IgE levels, and specific IgE for Aspergillus fumigatus hinted at ABPA. Confirmation led to a successful three-month oral steroid course, combining therapies for effective management. Distinguishing ABPA from asthma and infections demands a thorough approach for timely identification and treatment in pediatric cases.

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