混合式与开放式食管癌切除术的手术效果对比分析:俄罗斯地区癌症中心的经验

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Evgeny Toneev, Oleg Aleksandrov, Oleg Pikin, Lyudmila Danilova, Oleg Midlenko, Vladimir Midlenko, Andrey Chavga
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引用次数: 0

摘要

手术是治疗食管癌的关键;结合了微创和开放技术的混合食管切除术显示出良好的疗效。这项历史性队列研究比较了标准开放式食管切除术和混合式食管切除术的手术效果。研究共纳入了 2015 年 1 月至 2023 年 12 月期间在俄罗斯乌里扬诺夫斯克地区临床肿瘤诊所接受混合或开放式食管切除术的 58 名患者。对人口统计学、手术细节和术后结果等数据进行了分析。主要衡量指标为总体并发症和吻合口漏率。统计分析通过 StatTech 软件(2.8.8 版)使用皮尔逊卡方检验和 t 检验进行。杂交组切除的淋巴结数量(24±9)个高于开放组(15±7)个(P
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative Analysis of Surgical Outcomes in Hybrid and Open Esophagectomy for Esophageal Cancer: A Regional Russian Cancer Centre Experience.

Surgery is pivotal in treating esophageal cancer; hybrid esophagectomy, which combines minimally invasive and open techniques, shows promising outcomes. This historical cohort study compared the surgical outcomes of standard open esophagectomy with hybrid esophagectomy. Overall, 58 patients who underwent either hybrid or open esophagectomy at the Ulyanovsk Regional Clinical Oncology Clinic, Russia, from January 2015 to December 2023 were included. Data on demographics, surgical details, and postoperative outcomes were analyzed. The primary measures were overall complications and anastomotic leakage rates. Statistical analysis was performed using Pearson's Chi square test and t test via StatTech software (version 2.8.8). The number of removed lymph nodes was higher in the hybrid group (24±9) than in the open group (15±7) (P<0.001). In addition, the hybrid esophagectomy group showed significant reductions in operational time and blood loss (P<0.001 and P=0.014, respectively). The need for blood transfusion was higher in the open esophagectomy group (P=0.043). The postoperative length of stay in the hospital did not differ significantly between the two groups (open=20±8 days, hybrid=17±7 days, P=0.178). Cardiac complications were more frequent after an open esophagectomy (P=0.044). Hybrid esophagectomy reduced postoperative cardiac complications and other adverse events while maintaining satisfactory oncological outcomes. It had advantages over standard open esophagectomy in terms of lymphadenectomy, operative time, blood loss, and transfusion requirements, suggesting its efficacy for esophageal cancer patients.

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来源期刊
Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
0.00%
发文量
84
审稿时长
12 weeks
期刊介绍: The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of com­muni­cation for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science re­search experiences on prevalent diseases in the region and analysis of various regional problems.
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