Qing-Yu Lu , Zhao-Jie Wang , Li-Yu Bai , Wen-Biao Zu , Zhong-Shun Zhou , Yan-Yan Zhu , Xing-Chao He , Yun-Li Zhao , Xiao-Dong Luo
{"title":"Caryopteris trichosphaera 中的两种新的abietane diterpenoids。","authors":"Qing-Yu Lu , Zhao-Jie Wang , Li-Yu Bai , Wen-Biao Zu , Zhong-Shun Zhou , Yan-Yan Zhu , Xing-Chao He , Yun-Li Zhao , Xiao-Dong Luo","doi":"10.1016/j.fitote.2024.106269","DOIUrl":null,"url":null,"abstract":"<div><div>Two new abietane diterpenoids, cartrisine A (<strong>1</strong>) and cartrisine B (<strong>2</strong>) were isolated from <em>Caryopteris trichosphaera</em>. Their structures were elucidated based on HR-ESI-MS and NMR spectral data. Compound <strong>2</strong> exhibited moderate antibacterial bioactivity against MRSA and VRE, and showed a strong synergistic effect with market antibiotics against MRSA and VRE.</div></div>","PeriodicalId":12147,"journal":{"name":"Fitoterapia","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Two new abietane diterpenoids from Caryopteris trichosphaera\",\"authors\":\"Qing-Yu Lu , Zhao-Jie Wang , Li-Yu Bai , Wen-Biao Zu , Zhong-Shun Zhou , Yan-Yan Zhu , Xing-Chao He , Yun-Li Zhao , Xiao-Dong Luo\",\"doi\":\"10.1016/j.fitote.2024.106269\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Two new abietane diterpenoids, cartrisine A (<strong>1</strong>) and cartrisine B (<strong>2</strong>) were isolated from <em>Caryopteris trichosphaera</em>. Their structures were elucidated based on HR-ESI-MS and NMR spectral data. Compound <strong>2</strong> exhibited moderate antibacterial bioactivity against MRSA and VRE, and showed a strong synergistic effect with market antibiotics against MRSA and VRE.</div></div>\",\"PeriodicalId\":12147,\"journal\":{\"name\":\"Fitoterapia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fitoterapia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0367326X24004520\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fitoterapia","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0367326X24004520","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Two new abietane diterpenoids from Caryopteris trichosphaera
Two new abietane diterpenoids, cartrisine A (1) and cartrisine B (2) were isolated from Caryopteris trichosphaera. Their structures were elucidated based on HR-ESI-MS and NMR spectral data. Compound 2 exhibited moderate antibacterial bioactivity against MRSA and VRE, and showed a strong synergistic effect with market antibiotics against MRSA and VRE.
期刊介绍:
Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas:
1. Characterization of active ingredients of medicinal plants
2. Development of standardization method for bioactive plant extracts and natural products
3. Identification of bioactivity in plant extracts
4. Identification of targets and mechanism of activity of plant extracts
5. Production and genomic characterization of medicinal plants biomass
6. Chemistry and biochemistry of bioactive natural products of plant origin
7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.