Daniella Cristo Santin, Isabella Dorigheto de Souza, Ana Carolina Cunha Rodrigues, Mylena Proença Costa, Thalyta Khetly Cardoso da Silva, Marina Ciccone Giacomini, Paulo Sérgio da Silva Santos, Linda Wang
{"title":"放疗后牙本质上自酸蚀粘接系统的效果：微拉伸和微剪切粘接强度的视角。","authors":"Daniella Cristo Santin, Isabella Dorigheto de Souza, Ana Carolina Cunha Rodrigues, Mylena Proença Costa, Thalyta Khetly Cardoso da Silva, Marina Ciccone Giacomini, Paulo Sérgio da Silva Santos, Linda Wang","doi":"10.1007/s00784-024-05994-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Self-etching dental adhesives bond with dentin through chemical reactions with calcium. This study assessed bond strength (BS) using microtensile (µTBS) and microshear (µSBS) tests on sound and post-radiotherapy dentin, with dental adhesives containing different functional monomers.</p><p><strong>Methods: </strong>Sound dentin (SD) and post-radiotherapy irradiated dentin (ID) were tested with two adhesive systems: Clearfil SE Bond (SE, 10-MDP-based) and FL Bond II (FL, containing carboxylic and phosphonic monomers with S-PRG bioactive particles). The tests occurred initially (24 h) and six months later; fracture mode was also analyzed (40x). Ninety-six human molars were randomly assigned (n = 12), and half were irradiated with a 70 Gy radiation dose. For µTBS test, teeth were bonded, restored and sectioned them into beams (0.64 mm<sup>2</sup>). The µSBS test used filled transparent cylindrical matrices with resin composite and light-cured them after dental adhesive applications. Three-way ANOVA and Tukey's test (p < 0.05) analyzed the data.</p><p><strong>Results: </strong>µTBS showed a significant substrate x adhesive interaction (p < 0.001), while µSBS was significant for all factors (p = 0.006). SE and FL performed better on SD and ID, respectively, in the µTBS test. As for µSBS, SE showed higher values on ID (p < 0.05). Lower BS values occurred for SD-FL and ID-SE after six months.</p><p><strong>Conclusion: </strong>Dental adhesive performance varied based on substrate type and test method. FL was more stable for ID in µTBS, while SE excelled in µSBS.</p><p><strong>Clinical relevance: </strong>As post-radiotherapy irradiated dentin becomes more vulnerable, self-etching systems based on functional monomer and bioactive ingredients may exhibit appropriate bonding to this altered substrate.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"28 11","pages":"611"},"PeriodicalIF":3.1000,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effectiveness of self-etching bonding systems on dentin after radiotherapy: perspectives on microtensile and microshear bond strength.\",\"authors\":\"Daniella Cristo Santin, Isabella Dorigheto de Souza, Ana Carolina Cunha Rodrigues, Mylena Proença Costa, Thalyta Khetly Cardoso da Silva, Marina Ciccone Giacomini, Paulo Sérgio da Silva Santos, Linda Wang\",\"doi\":\"10.1007/s00784-024-05994-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Self-etching dental adhesives bond with dentin through chemical reactions with calcium. This study assessed bond strength (BS) using microtensile (µTBS) and microshear (µSBS) tests on sound and post-radiotherapy dentin, with dental adhesives containing different functional monomers.</p><p><strong>Methods: </strong>Sound dentin (SD) and post-radiotherapy irradiated dentin (ID) were tested with two adhesive systems: Clearfil SE Bond (SE, 10-MDP-based) and FL Bond II (FL, containing carboxylic and phosphonic monomers with S-PRG bioactive particles). The tests occurred initially (24 h) and six months later; fracture mode was also analyzed (40x). Ninety-six human molars were randomly assigned (n = 12), and half were irradiated with a 70 Gy radiation dose. For µTBS test, teeth were bonded, restored and sectioned them into beams (0.64 mm<sup>2</sup>). The µSBS test used filled transparent cylindrical matrices with resin composite and light-cured them after dental adhesive applications. Three-way ANOVA and Tukey's test (p < 0.05) analyzed the data.</p><p><strong>Results: </strong>µTBS showed a significant substrate x adhesive interaction (p < 0.001), while µSBS was significant for all factors (p = 0.006). SE and FL performed better on SD and ID, respectively, in the µTBS test. As for µSBS, SE showed higher values on ID (p < 0.05). Lower BS values occurred for SD-FL and ID-SE after six months.</p><p><strong>Conclusion: </strong>Dental adhesive performance varied based on substrate type and test method. FL was more stable for ID in µTBS, while SE excelled in µSBS.</p><p><strong>Clinical relevance: </strong>As post-radiotherapy irradiated dentin becomes more vulnerable, self-etching systems based on functional monomer and bioactive ingredients may exhibit appropriate bonding to this altered substrate.</p>\",\"PeriodicalId\":10461,\"journal\":{\"name\":\"Clinical Oral Investigations\",\"volume\":\"28 11\",\"pages\":\"611\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2024-10-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Oral Investigations\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00784-024-05994-8\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Oral Investigations","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00784-024-05994-8","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
目的：自酸蚀牙科粘合剂通过与钙的化学反应与牙本质粘合。本研究使用微拉伸（µTBS）和微剪切（µSBS）测试评估了含有不同功能单体的牙科粘合剂在健全牙本质和放射治疗后牙本质上的粘合强度（BS）：方法：使用两种粘合剂系统对健全牙本质（SD）和放射治疗后照射牙本质（ID）进行测试：Clearfil SE Bond（SE，基于 10-MDP）和 FL Bond II（FL，含有羧基和膦基单体以及 S-PRG 生物活性颗粒）。测试分别在最初（24 小时）和六个月后进行；还对断裂模式进行了分析（40 倍）。96 颗人类臼齿被随机分配（n = 12），其中一半受到 70 Gy 放射剂量的照射。在 µTBS 试验中，牙齿被粘接、修复并切成横梁（0.64 平方毫米）。µSBS测试使用树脂复合材料填充透明圆柱形基质，并在涂抹牙科粘合剂后进行光固化。三方方差分析和 Tukey's 检验（p 结果：µTBS 显示基质与粘合剂之间存在明显的交互作用（p 结论：粘合剂的性能因基质和粘合剂的不同而不同：牙科粘合剂的性能因基底类型和测试方法而异。FL 在 µTBS 中对 ID 更为稳定，而 SE 在 µSBS 中表现优异：临床意义：随着放射治疗后照射过的牙本质变得更加脆弱，基于功能性单体和生物活性成分的自酸蚀系统可能会对这种改变的基质产生适当的粘接效果。
Effectiveness of self-etching bonding systems on dentin after radiotherapy: perspectives on microtensile and microshear bond strength.
Objective: Self-etching dental adhesives bond with dentin through chemical reactions with calcium. This study assessed bond strength (BS) using microtensile (µTBS) and microshear (µSBS) tests on sound and post-radiotherapy dentin, with dental adhesives containing different functional monomers.
Methods: Sound dentin (SD) and post-radiotherapy irradiated dentin (ID) were tested with two adhesive systems: Clearfil SE Bond (SE, 10-MDP-based) and FL Bond II (FL, containing carboxylic and phosphonic monomers with S-PRG bioactive particles). The tests occurred initially (24 h) and six months later; fracture mode was also analyzed (40x). Ninety-six human molars were randomly assigned (n = 12), and half were irradiated with a 70 Gy radiation dose. For µTBS test, teeth were bonded, restored and sectioned them into beams (0.64 mm2). The µSBS test used filled transparent cylindrical matrices with resin composite and light-cured them after dental adhesive applications. Three-way ANOVA and Tukey's test (p < 0.05) analyzed the data.
Results: µTBS showed a significant substrate x adhesive interaction (p < 0.001), while µSBS was significant for all factors (p = 0.006). SE and FL performed better on SD and ID, respectively, in the µTBS test. As for µSBS, SE showed higher values on ID (p < 0.05). Lower BS values occurred for SD-FL and ID-SE after six months.
Conclusion: Dental adhesive performance varied based on substrate type and test method. FL was more stable for ID in µTBS, while SE excelled in µSBS.
Clinical relevance: As post-radiotherapy irradiated dentin becomes more vulnerable, self-etching systems based on functional monomer and bioactive ingredients may exhibit appropriate bonding to this altered substrate.
期刊介绍：
The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
