与 HIV 相关的污名化对儿童和年轻成人 HIV 感染者坚持抗逆转录病毒治疗、参与和坚持 HIV 护理以及向成人 HIV 护理过渡的影响》（Impact of HIV-Related Stigma on Antiretroviral Therapy Adherence, Engagement and Retention in HIV Care, and Transition to Adult HIV Care in Pediatric and Young Adult Populations Living With HIV）：文献综述。
IF 2.7 2区 医学Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Teodora Perger, Mariam Davtyan, Caroline Foster, Michael Evangeli, Claire Berman, Deborah Kacanek, Ana M Puga, Serufusa Sekidde, Sanj Bhopal
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引用次数: 0
摘要
在儿童和年轻的成人艾滋病病毒感染者中，与艾滋病相关的污名化与心理健康的负面影响和健康相关生活质量的降低有关。我们回顾了有关 HIV 相关污名对儿童、青少年和年轻成人 HIV 感染者的抗逆转录病毒疗法（ART）次优依从性、参与和保留 HIV 护理以及向成人 HIV 护理过渡的影响的文献。在 PubMed 和 Embase® 中检索了 2012 年 1 月 1 日至 2023 年 4 月 13 日期间发表的报告相关数据的出版物。结果并非系统性综述，而是有针对性的文献综述。根据预先指定的标准（如质量），共选择了 67 项研究进行分析。大多数定量研究支持儿科和年轻成人 HIV 感染者中 HIV 相关污名与坚持抗逆转录病毒疗法（n = 8/11）、参与和坚持 HIV 护理（n = 3/4）以及过渡到成人 HIV 护理（n = 2/3）之间存在负相关。定性研究报告称，污名化是坚持抗逆转录病毒疗法（26 例）、参与和坚持 HIV 护理（18 例）以及过渡到成人 HIV 护理（11 例）的障碍。在所有主题中，突出的访谈主题包括预期的污名化、实际的污名化以及对披露 HIV 感染状况的恐惧。研究结果再次证实，与艾滋病相关的污名化对坚持抗逆转录病毒疗法、参与和继续接受艾滋病护理，以及在儿科和年轻的成人艾滋病感染者中过渡到成人艾滋病护理是一个重大障碍，可能会影响病毒学抑制、继续传播和长期健康。我们需要开展更多的干预性研究，以评估和减少污名化对这些重要人群的影响。
Impact of HIV-Related Stigma on Antiretroviral Therapy Adherence, Engagement and Retention in HIV Care, and Transition to Adult HIV Care in Pediatric and Young Adult Populations Living With HIV: A Literature Review.
HIV-related stigma is associated with negative effects on mental health and lower health-related quality of life in pediatric and young adult populations living with HIV. We reviewed literature on the impact of HIV-related stigma on suboptimal antiretroviral therapy (ART) adherence, engagement and retention in HIV care, and transition to adult HIV care in children, adolescents, and young adults living with HIV. PubMed and Embase® were searched for publications reporting relevant data published from January 1, 2012, to April 13, 2023. The output was not a systematic review; it was a targeted literature review. Overall, 67 studies were selected for analysis based on pre-specified criteria (eg, quality). Most quantitative studies supported negative associations between HIV-related stigma and ART adherence (n = 8/11), engagement and retention in HIV care (n = 3/4), and transition to adult HIV care (n = 2/3) in pediatric and young adult populations living with HIV. Qualitative studies reported that stigma was a barrier to ART adherence (n = 26), engagement and retention in HIV care (n = 18), and transitioning to adult HIV care (n = 11). Prominent interview themes across all topics included anticipated stigma, enacted stigma, and fear of HIV status disclosure. Results reaffirm that HIV-related stigma is a significant barrier to ART adherence, engagement and retention in HIV care, and transition to adult HIV care among pediatric and young adult populations living with HIV, potentially impacting virologic suppression, onward transmission, and longer-term health. Additional interventional studies are needed to evaluate and reduce the impact of stigma in these important populations.
期刊介绍：
AIDS and Behavior provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews. provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews.5 Year Impact Factor: 2.965 (2008) Section ''SOCIAL SCIENCES, BIOMEDICAL'': Rank 5 of 29 Section ''PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH'': Rank 9 of 76
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