通过钯介导的吲哚基三氟酸盐与芳基乙炔的 Sonogashira 偶联合成二/三代咔唑。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Rudrasenan Agneswaran, Arasambattu K Mohanakrishnan
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引用次数: 0

摘要

在本研究中,我们介绍了合成咔唑衍生物的初步发现,包括 2-(三甲基氨基)甲基吲哚三氟酸盐与芳基乙炔的 Sonogashira 偶联反应,然后进行异构化、热电环化和 1,3-H 变换,得到相应的二取代咔唑和三取代咔唑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis of di/tri-substituted carbazoles involving Pd-mediated Sonogashira coupling of indolyltriflates with aryl acetylenes.

In this study, we present our preliminary findings on the synthesis of carbazole derivatives involving the Sonogashira coupling reaction of 2-(trimethylamino)methylindolyltriflates with aryl acetylenes followed by isomerization, thermal electrocyclization and 1,3-H shift, furnishing the respective di- and tri-substituted carbazoles.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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