钯催化 C-H 键活化和脱羧以组装吲哚并[1,2-f]菲啶。

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2024-09-02 DOI:10.1039/d4ob01383b

Xiaobing Liu , Yong-Liang Ban , Yanjie Liu , Mengdie Zhuang , Yao Zhou

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引用次数: 0

摘要

本文介绍了一种通过 Pd 催化的串联环化反应组装吲哚并[1,2-f]菲啶的直接而方便的策略。目前的策略利用现成的 1-(2-碘苯基)-1H-吲哚和市售的邻溴苯甲酸作为起始原料，提供了一系列吲哚并[1,2-f]菲啶衍生物。该反应的特点是通过钯催化 C-H 键活化和脱羧形成两个 C-C 键。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Palladium-catalyzed C–H bond activation and decarboxylation for the assembly of indolo[1,2-f]phenanthridine†

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Palladium-catalyzed C–H bond activation and decarboxylation for the assembly of indolo[1,2-f]phenanthridine†

A direct and convenient strategy for the assembly of indolo[1,2-f]phenanthridine via a Pd-catalyzed tandem cyclization reaction is presented. The current strategy delivers a range of indolo[1,2-f]phenanthridine derivatives by utilizing readily available 1-(2-iodophenyl)-1H-indole and commercially available o-bromobenzoic acids as the starting materials. The reaction features the formation of two C–C bonds through Pd-catalyzed C–H bond activation and decarboxylation.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.