通过酶活性分析发现表观遗传学

IF 81.3 1区生物学 Q1 CELL BIOLOGY

Nature Reviews Molecular Cell Biology Pub Date : 2024-10-25 DOI:10.1038/s41580-024-00801-4

Manini S. Penikalapati, Jordan L. Meier

引用次数: 0

摘要

C.戴维-阿里斯从四膜虫中发现了第一个组蛋白乙酰转移酶，这一发现体现了一种不断发展的方法，如今它在药物开发中发挥着至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epigenetic discovery by enzyme activity profiling

C. David Allis’s discovery of the first histone acetyltransferase from Tetrahymena exemplifies an approach that continues to evolve and now has a crucial role in drug development.

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来源期刊

Nature Reviews Molecular Cell Biology 生物-细胞生物学

CiteScore

173.60

自引率

0.50%

发文量

118

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Molecular Cell Biology is a prestigious journal that aims to be the primary source of reviews and commentaries for the scientific communities it serves. The journal strives to publish articles that are authoritative, accessible, and enriched with easily understandable figures, tables, and other display items. The goal is to provide an unparalleled service to authors, referees, and readers, and the journal works diligently to maximize the usefulness and impact of each article. Nature Reviews Molecular Cell Biology publishes a variety of article types, including Reviews, Perspectives, Comments, and Research Highlights, all of which are relevant to molecular and cell biologists. The journal's broad scope ensures that the articles it publishes reach the widest possible audience.