Andrea Brunelli, A. Serrano-Lotina, Miguel Bañares, Victor Alcolea-Rodriguez, Magda Blosi, Anna Costa, Simona Ortelli, Willie Peijnenburg, Carlos Fito-López, Ernesto Gonzalez Fernandez, Jorge Hermosilla, Lya G Soeteman-Hernandez, Iranztu Garmendia Aguirre, Hubert Rauscher, Fiona Murphy, Vicki Stone, José Balbuena, José Manuel Lloris Cormano, Lisa Pizzol, Danail Hristozov, Antonio Marcomini, Elena Badetti
{"title":"对建筑中使用的 SiO2@ZnO 多组分纳米材料进行安全设计评估","authors":"Andrea Brunelli, A. Serrano-Lotina, Miguel Bañares, Victor Alcolea-Rodriguez, Magda Blosi, Anna Costa, Simona Ortelli, Willie Peijnenburg, Carlos Fito-López, Ernesto Gonzalez Fernandez, Jorge Hermosilla, Lya G Soeteman-Hernandez, Iranztu Garmendia Aguirre, Hubert Rauscher, Fiona Murphy, Vicki Stone, José Balbuena, José Manuel Lloris Cormano, Lisa Pizzol, Danail Hristozov, Antonio Marcomini, Elena Badetti","doi":"10.1039/d4en00352g","DOIUrl":null,"url":null,"abstract":"Safety aspects of chemicals/materials are transversal in all sustainability dimensions, representing a pillar at early-innovation stages of the European Commission’s “Safe and Sustainable-by-Design” (SSbD) framework for chemicals and materials. The first three of the five SSbD framework steps covers different safety aspects: hazard assessment based on intrinsic properties (step 1), occupational health and safety (including exposure) assessment during the production/processing phase (step 2) and exposure in the final application phase (step 3). The goal of this work was to identify a set of characterization tools/procedures to support the operationalization of the first three safety steps to multi-component nanomaterials (MCNMs), applying the findings to a SiO2<small><sub></sub></small> core-ZnO shell MCNM. The safety of this MCNM, used as additive to a silicate/calcium hydroxide mortar to improve air quality through photocatalytic NOₓ removal, was investigated from different perspectives along its value chain. Existing and newly generated data on its hazard profile were collected, workers’ exposure during synthesis was assessed, and potential exposure to hazardous substances during its final application phase was investigated. Concerning step 1, physico-chemical properties, hazard classification and cytotoxicity assays were considered. Afterwards, a three-tiered established methodology for evaluating occupational exposure assessment was performed for step 2. Lastly, for step 3, the release of inorganic substances from the MCNM-based mortars in the final application phase was investigated. Safety assessment according to the SSbD framework was done by selecting tools and procedures suitable for application at an early innovation stage, resulting in a preliminary hazard assessment of the MCNM and a suggestion for redesigning a step in the process.","PeriodicalId":73,"journal":{"name":"Environmental Science: Nano","volume":"125 1","pages":""},"PeriodicalIF":5.8000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Safe-by-design assessment of SiO2@ZnO multi-component nanomaterial used in construction\",\"authors\":\"Andrea Brunelli, A. Serrano-Lotina, Miguel Bañares, Victor Alcolea-Rodriguez, Magda Blosi, Anna Costa, Simona Ortelli, Willie Peijnenburg, Carlos Fito-López, Ernesto Gonzalez Fernandez, Jorge Hermosilla, Lya G Soeteman-Hernandez, Iranztu Garmendia Aguirre, Hubert Rauscher, Fiona Murphy, Vicki Stone, José Balbuena, José Manuel Lloris Cormano, Lisa Pizzol, Danail Hristozov, Antonio Marcomini, Elena Badetti\",\"doi\":\"10.1039/d4en00352g\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Safety aspects of chemicals/materials are transversal in all sustainability dimensions, representing a pillar at early-innovation stages of the European Commission’s “Safe and Sustainable-by-Design” (SSbD) framework for chemicals and materials. The first three of the five SSbD framework steps covers different safety aspects: hazard assessment based on intrinsic properties (step 1), occupational health and safety (including exposure) assessment during the production/processing phase (step 2) and exposure in the final application phase (step 3). The goal of this work was to identify a set of characterization tools/procedures to support the operationalization of the first three safety steps to multi-component nanomaterials (MCNMs), applying the findings to a SiO2<small><sub></sub></small> core-ZnO shell MCNM. The safety of this MCNM, used as additive to a silicate/calcium hydroxide mortar to improve air quality through photocatalytic NOₓ removal, was investigated from different perspectives along its value chain. Existing and newly generated data on its hazard profile were collected, workers’ exposure during synthesis was assessed, and potential exposure to hazardous substances during its final application phase was investigated. Concerning step 1, physico-chemical properties, hazard classification and cytotoxicity assays were considered. Afterwards, a three-tiered established methodology for evaluating occupational exposure assessment was performed for step 2. Lastly, for step 3, the release of inorganic substances from the MCNM-based mortars in the final application phase was investigated. 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Safe-by-design assessment of SiO2@ZnO multi-component nanomaterial used in construction
Safety aspects of chemicals/materials are transversal in all sustainability dimensions, representing a pillar at early-innovation stages of the European Commission’s “Safe and Sustainable-by-Design” (SSbD) framework for chemicals and materials. The first three of the five SSbD framework steps covers different safety aspects: hazard assessment based on intrinsic properties (step 1), occupational health and safety (including exposure) assessment during the production/processing phase (step 2) and exposure in the final application phase (step 3). The goal of this work was to identify a set of characterization tools/procedures to support the operationalization of the first three safety steps to multi-component nanomaterials (MCNMs), applying the findings to a SiO2 core-ZnO shell MCNM. The safety of this MCNM, used as additive to a silicate/calcium hydroxide mortar to improve air quality through photocatalytic NOₓ removal, was investigated from different perspectives along its value chain. Existing and newly generated data on its hazard profile were collected, workers’ exposure during synthesis was assessed, and potential exposure to hazardous substances during its final application phase was investigated. Concerning step 1, physico-chemical properties, hazard classification and cytotoxicity assays were considered. Afterwards, a three-tiered established methodology for evaluating occupational exposure assessment was performed for step 2. Lastly, for step 3, the release of inorganic substances from the MCNM-based mortars in the final application phase was investigated. Safety assessment according to the SSbD framework was done by selecting tools and procedures suitable for application at an early innovation stage, resulting in a preliminary hazard assessment of the MCNM and a suggestion for redesigning a step in the process.
期刊介绍:
Environmental Science: Nano serves as a comprehensive and high-impact peer-reviewed source of information on the design and demonstration of engineered nanomaterials for environment-based applications. It also covers the interactions between engineered, natural, and incidental nanomaterials with biological and environmental systems. This scope includes, but is not limited to, the following topic areas:
Novel nanomaterial-based applications for water, air, soil, food, and energy sustainability
Nanomaterial interactions with biological systems and nanotoxicology
Environmental fate, reactivity, and transformations of nanoscale materials
Nanoscale processes in the environment
Sustainable nanotechnology including rational nanomaterial design, life cycle assessment, risk/benefit analysis