{"title":"婴儿变异链球菌和乳酸杆菌的早期口腔定植:调查婴儿从出生到 6 个月期间与母体和环境因素的关系。","authors":"Cansu Ay, Huseyin Karayılmaz, Ayse Cengiz","doi":"10.12669/pjms.40.9.9602","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the presence of <i>Streptococcus Mutans</i> (<i>S.mutans</i>) and <i>Lactobacillus</i> species (<i>LB</i>) of newborn-mother pairs using the real time polymerase chain reaction (qRT-PCR).</p><p><strong>Method: </strong>Subjects were selected from the patients followed in the Neonatology Clinic of Akdeniz University's Faculty of Medicine between the years 2017-2018. First samples collected within 48 hours after birth, and second samples were at six months. The samples were analyzed for the presence of <i>S.mutans</i> and <i>LB</i> using qRT-PCR. Mothers' smoking habits, education level, occupation, oral hygiene habits, DMFT scores and dietary history; Babies' delivery type, birth weight, feeding type, oral hygiene practices, feeding habits, bottle usage, pacifier usage, consumption of sugary foods, were also recorded. The effect of factors related to both mothers and infants was examined comparatively.</p><p><strong>Results: </strong><i>S.mutans</i> DNA was detectable in 87% and <i>LB</i> DNA was detected in 37% mothers, while it was undetected in 63% mothers at the first sampling. <i>S.mutans</i> was detected in 37% and, while <i>LB</i> was detected in 5% of the newborns in the first 48 hours of their life. At the second sampling, the <i>S.mutans</i> and <i>LB</i> levels in infants have increased, while there has been no significant change in mothers. A significant relationship was found only between the increase in <i>S.mutans</i> in infants and the presence of erupted teeth.</p><p><strong>Conclusion: </strong><i>S.mutans</i> and <i>LB</i> were able to colonize on the oral mucosal surfaces of edentulous newborns, with the counts of both bacteria increasing significantly with tooth eruption.</p>","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"40 9","pages":"2028-2035"},"PeriodicalIF":1.2000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476146/pdf/","citationCount":"0","resultStr":"{\"title\":\"Early oral colonization of streptococcus mutans and lactobacilli species in infants: Investigating the relationship with maternal and environmental factors, from birth through the sixth month.\",\"authors\":\"Cansu Ay, Huseyin Karayılmaz, Ayse Cengiz\",\"doi\":\"10.12669/pjms.40.9.9602\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To assess the presence of <i>Streptococcus Mutans</i> (<i>S.mutans</i>) and <i>Lactobacillus</i> species (<i>LB</i>) of newborn-mother pairs using the real time polymerase chain reaction (qRT-PCR).</p><p><strong>Method: </strong>Subjects were selected from the patients followed in the Neonatology Clinic of Akdeniz University's Faculty of Medicine between the years 2017-2018. First samples collected within 48 hours after birth, and second samples were at six months. The samples were analyzed for the presence of <i>S.mutans</i> and <i>LB</i> using qRT-PCR. Mothers' smoking habits, education level, occupation, oral hygiene habits, DMFT scores and dietary history; Babies' delivery type, birth weight, feeding type, oral hygiene practices, feeding habits, bottle usage, pacifier usage, consumption of sugary foods, were also recorded. The effect of factors related to both mothers and infants was examined comparatively.</p><p><strong>Results: </strong><i>S.mutans</i> DNA was detectable in 87% and <i>LB</i> DNA was detected in 37% mothers, while it was undetected in 63% mothers at the first sampling. <i>S.mutans</i> was detected in 37% and, while <i>LB</i> was detected in 5% of the newborns in the first 48 hours of their life. At the second sampling, the <i>S.mutans</i> and <i>LB</i> levels in infants have increased, while there has been no significant change in mothers. A significant relationship was found only between the increase in <i>S.mutans</i> in infants and the presence of erupted teeth.</p><p><strong>Conclusion: </strong><i>S.mutans</i> and <i>LB</i> were able to colonize on the oral mucosal surfaces of edentulous newborns, with the counts of both bacteria increasing significantly with tooth eruption.</p>\",\"PeriodicalId\":19958,\"journal\":{\"name\":\"Pakistan Journal of Medical Sciences\",\"volume\":\"40 9\",\"pages\":\"2028-2035\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476146/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pakistan Journal of Medical Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12669/pjms.40.9.9602\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12669/pjms.40.9.9602","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Early oral colonization of streptococcus mutans and lactobacilli species in infants: Investigating the relationship with maternal and environmental factors, from birth through the sixth month.
Objective: To assess the presence of Streptococcus Mutans (S.mutans) and Lactobacillus species (LB) of newborn-mother pairs using the real time polymerase chain reaction (qRT-PCR).
Method: Subjects were selected from the patients followed in the Neonatology Clinic of Akdeniz University's Faculty of Medicine between the years 2017-2018. First samples collected within 48 hours after birth, and second samples were at six months. The samples were analyzed for the presence of S.mutans and LB using qRT-PCR. Mothers' smoking habits, education level, occupation, oral hygiene habits, DMFT scores and dietary history; Babies' delivery type, birth weight, feeding type, oral hygiene practices, feeding habits, bottle usage, pacifier usage, consumption of sugary foods, were also recorded. The effect of factors related to both mothers and infants was examined comparatively.
Results: S.mutans DNA was detectable in 87% and LB DNA was detected in 37% mothers, while it was undetected in 63% mothers at the first sampling. S.mutans was detected in 37% and, while LB was detected in 5% of the newborns in the first 48 hours of their life. At the second sampling, the S.mutans and LB levels in infants have increased, while there has been no significant change in mothers. A significant relationship was found only between the increase in S.mutans in infants and the presence of erupted teeth.
Conclusion: S.mutans and LB were able to colonize on the oral mucosal surfaces of edentulous newborns, with the counts of both bacteria increasing significantly with tooth eruption.
期刊介绍:
It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad.
Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.