婴儿变异链球菌和乳酸杆菌的早期口腔定植:调查婴儿从出生到 6 个月期间与母体和环境因素的关系。

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Cansu Ay, Huseyin Karayılmaz, Ayse Cengiz
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引用次数: 0

摘要

目的使用实时聚合酶链反应(qRT-PCR)评估新生儿-母亲配对中是否存在变异链球菌(S.mutans)和乳酸杆菌(LB):研究对象选自阿克登尼兹大学医学院新生儿诊所 2017-2018 年间的随访患者。第一份样本在出生后 48 小时内采集,第二份样本在六个月后采集。使用 qRT-PCR 分析样本中是否存在 S.mutans 和 LB。此外,还记录了母亲的吸烟习惯、教育水平、职业、口腔卫生习惯、DMFT 评分和饮食史;婴儿的分娩方式、出生体重、喂养方式、口腔卫生习惯、喂养习惯、奶瓶使用情况、奶嘴使用情况、含糖食物摄入情况。比较研究了与母亲和婴儿有关的因素的影响:结果:在第一次采样时,87%的母亲能检测到 S.mutans DNA,37%的母亲能检测到 LB DNA,63%的母亲检测不到 S.mutans DNA。在新生儿出生后的 48 小时内,37% 的新生儿检测到 S.mutans,5% 的新生儿检测到 LB。在第二次采样中,婴儿体内的变异杆菌和枸橼酸含量有所上升,而母亲体内的含量没有明显变化。只有在婴儿的变异杆菌含量增加与牙齿是否萌出之间发现了明显的关系:结论:变异杆菌和枸橼酸杆菌能够在无牙新生儿的口腔黏膜表面定植,这两种细菌的数量随着牙齿萌出而显著增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early oral colonization of streptococcus mutans and lactobacilli species in infants: Investigating the relationship with maternal and environmental factors, from birth through the sixth month.

Objective: To assess the presence of Streptococcus Mutans (S.mutans) and Lactobacillus species (LB) of newborn-mother pairs using the real time polymerase chain reaction (qRT-PCR).

Method: Subjects were selected from the patients followed in the Neonatology Clinic of Akdeniz University's Faculty of Medicine between the years 2017-2018. First samples collected within 48 hours after birth, and second samples were at six months. The samples were analyzed for the presence of S.mutans and LB using qRT-PCR. Mothers' smoking habits, education level, occupation, oral hygiene habits, DMFT scores and dietary history; Babies' delivery type, birth weight, feeding type, oral hygiene practices, feeding habits, bottle usage, pacifier usage, consumption of sugary foods, were also recorded. The effect of factors related to both mothers and infants was examined comparatively.

Results: S.mutans DNA was detectable in 87% and LB DNA was detected in 37% mothers, while it was undetected in 63% mothers at the first sampling. S.mutans was detected in 37% and, while LB was detected in 5% of the newborns in the first 48 hours of their life. At the second sampling, the S.mutans and LB levels in infants have increased, while there has been no significant change in mothers. A significant relationship was found only between the increase in S.mutans in infants and the presence of erupted teeth.

Conclusion: S.mutans and LB were able to colonize on the oral mucosal surfaces of edentulous newborns, with the counts of both bacteria increasing significantly with tooth eruption.

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来源期刊
Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences 医学-医学:内科
CiteScore
4.10
自引率
9.10%
发文量
363
审稿时长
3-6 weeks
期刊介绍: It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.
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