酵母基因 ECM9 在应激条件下调节细胞壁的维护和细胞分裂。

microPublication biology Pub Date : 2024-10-01 eCollection Date: 2024-01-01 DOI:10.17912/micropub.biology.001313
Prevena Ramakrishnan, Jill Keeney
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引用次数: 0

摘要

贝克酵母(Saccharomyces cerevisiae)是一种经过深入研究的真核生物模式。我们对真核细胞功能的了解大多来自酵母研究,但仍有近 10%的酵母基因尚未定性。本研究的重点是 YKR004C,它是一个已验证的未知功能基因,名为 ECM9,根据以前的研究预测,它参与细胞分裂和细胞壁的维护或组成。与野生型相比,我们研究了 ECM9 缺失菌株在胁迫条件下对细胞壁完整性的敏感性。这些结果表明,ECM9 参与了细胞壁的维护以及决定应激条件下细胞分裂准备状态的调节途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The yeast gene ECM9 regulates cell wall maintenance and cell division in stress conditions.

Saccharomyces cerevisiae , Baker's yeast, is a well-studied model eukaryotic organism. Much of our knowledge about eukaryotic cell function comes from yeast studies, though nearly 10% of yeast genes remain uncharacterized. This study focuses on YKR004C, a verified gene of unknown function named ECM9 , predicted to be involved in cell division and cell wall maintenance or composition based on previous studies. We investigated the sensitivity in stress conditions of an ECM9 deletion strain, compared to wild-type, to cell wall integrity. These results suggest that ECM9 is involved in cell wall maintenance and the regulatory pathway determining cell division readiness under stress.

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