George A Komnos, Tom Meade, Mohammadmahdi Sarzaeem, Mark Spangehl, Goksel Dikmen, Nifon K Gkekas, İbrahim Azboy, Roshan P Shah
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Is there a difference in the outcome of primary total knee arthroplasty performed using kinematic versus mechanical alignment?
Response/recommendation: Kinematic alignment (KA) shows improved patient-reported outcome measurements (PROMs) in early recovery but equivalence past mid-term follow-up. KA targets a native joint line obliquity and reapproximates pre-arthritic alignment, thus less soft-tissue adjustment may account for early differences. Several randomized controlled trials (RCTs) and systematic reviews fail to identify a durable clinically meaningful difference; Future non-commercial, non-biased, level-one studies are needed to elucidate long-term clinical outcomes and cost-effectiveness.
期刊介绍:
The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.