全关节关节置换术后是否会出现总体体重、体重指数或临床上显著的体重变化?对 60837 名患者的 Meta 分析。

IF 3.4 2区 医学 Q1 ORTHOPEDICS
Michael S Ramos, Martina E Hale, Pedro J Rullán, Kyle N Kunze, Nikhil Nair, Nicolas S Piuzzi
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引用次数: 0

摘要

背景:全关节置换术(TJA)可改善骨关节炎患者的生活质量和功能预后,这一点已得到广泛认可;但全关节置换术对体重的影响仍不明确。最近的趋势表明,TJA 患者正在发生变化,体重指数(BMI)较高的患者正在接受这种常见的手术。鉴于这一趋势,确定 TJA 对体重/BMI 的影响至关重要。本荟萃分析旨在定量评估 TJA 术后患者的体重/BMI 是减轻、增加还是保持不变:本研究遵循了 2020 年《系统综述和荟萃分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)指南。纳入的研究:(1)报告了择期、初次全髋关节置换术(THA)或全膝关节置换术(TKA)后的体重或 BMI;(2)体重/BMI 变化被认为与 THA/TKA 相关。排除的研究:(1)包括体重/BMI干预;(2)报告了单间室/部分关节置换术、翻修关节置换术或关节镜检查。使用随机效应模型对体重变化、BMI变化和实现临床显著变化的患者比例进行了元分析。系统报告了与临床显著变化相关的因素。共纳入了 39 项研究的 60837 名患者:结果:THA或TKA术后,术前和术后体重(P = 1.0;P = 0.28)或体重指数(P = 1.0;P = 1.0)分别无明显差异。总体而言,66% 的 THA 患者(P < 0.01)和 65% 的 TKA 患者(P < 0.01)的体重没有发生明显的临床变化。据报道,年龄、术前体重指数(BMI)和性别最常与临床上显著的体重/BMI变化有关:结论:三分之二接受 TJA 手术的患者在术后保持了术前体重/BMI。根据这些结果,骨科医生可以更好地管理患者对 TJA 的期望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Do Overall Weight, Body Mass Index, or Clinically Significant Weight Changes Occur After Total Joint Arthroplasty? A Meta-Analysis of 60,837 Patients.

Background: Total joint arthroplasty (TJA) is well-recognized for improving quality of life and functional outcomes of patients with osteoarthritis; however, TJA's impact on body weight remains unclear. Recent trends have demonstrated a shift among TJA patients, such that patients who have higher body mass indices (BMIs) are undergoing this common surgery. Given this trend, it is critical to characterize the impact TJA has on body weight or BMI. This meta-analysis aimed to quantitatively assess whether patients lose, gain, or maintain body weight or BMI after TJA.

Methods: This study followed the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Ovid MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials databases were queried from inception through July 2022. The included studies: (1) reported on weight or BMI after elective, primary total hip arthroplasty (THA) or total knee arthroplasty (TKA); and (2) weight or BMI change was deemed to be associated with THA or TKA. The excluded studies: (1) included weight or BMI interventions; and (2) reported on unicompartmental, partial, or revision arthroplasty or joint arthroscopy. Meta-analyses for weight change, BMI change, and proportion of patients achieving clinically significant change were performed using random-effects models. Factors associated with clinically significant change were systematically reported. A total of 60,837 patients from 39 studies were included.

Results: No significant differences existed between preoperative and postoperative weights (P = 1.0; P = 0.28) or BMIs (P = 1.0; P = 1.0) after THA or TKA, respectively. Overall, 66% of THA patients (P < 0.01) and 65% of TKA patients (P < 0.01) did not experience clinically significant weight change.

Conclusions: Among a TJA cohort, two-thirds of the patients maintained their preoperative body weight or BMI after surgery. With these results, orthopaedic surgeons can better manage patient expectations of TJA.

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来源期刊
Journal of Arthroplasty
Journal of Arthroplasty 医学-整形外科
CiteScore
7.00
自引率
20.00%
发文量
734
审稿时长
48 days
期刊介绍: The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.
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