声门上指数：哮喘患者对喉咽反流疗法反应的指标。

IF 5.8 2区医学 Q1 ALLERGY

Annals of Allergy Asthma & Immunology Pub Date : 2025-02-01 DOI:10.1016/j.anai.2024.10.012

Laurie A. Manka MD , Vamsi P. Guntur MD, MSc , Allen D. Stevens BA , Christena Kolakowski MS , Camille M. Moore PhD , Richard J. Martin MD

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引用次数: 0

摘要

背景：喉咽反流（LPR）与胃食管反流（GERD）有关，已知会导致哮喘控制不佳。LPR 和哮喘经常在同一个人身上同时存在。控制 LPR 可能与改善哮喘控制有关。声门上指数（SGI）是一种临床应用的视觉量表，与 LPR 的存在相关。SGI 在监测哮喘患者 LPR 治疗方面的作用尚不清楚：目标：SGI 是否可长期用于评估哮喘患者是否存在 LPR，SGI 是否会随着 LPR 治疗而改善？这是一项针对 15 名哮喘患者的试点研究。通过 SGI 测量未发现 LPR 的参与者被分配到观察组。有 LPR 的患者被分配到治疗组，接受标准的 LPR 治疗（抗酸剂和行为管理）或新型疗法（食管上辅助装置）：接受 8 周观察的哮喘患者的 SGI 保持稳定。结论：SGI 是一项可用于临床试验的指标：结论：SGI 是一种易于使用的临床工具，可用于评估是否存在 LPR 以及监测哮喘患者的治疗情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Supraglottic Index

Background

Laryngopharyngeal reflux (LPR) is associated with gastroesophageal reflux and is known to cause poor asthma control. Moreover, LPR and asthma frequently coexist in the same individual. Controlling LPR could be associated with improved asthma control. The Supraglottic Index (SGI) is a clinically applied visual scale, which correlates with the presence of LPR. The role of SGI in monitoring LPR therapy in individuals with asthma is not known.

Objective

To determine whether the SGI can be used over time to assess the presence of LPR in patients with asthma, and whether the SGI improves with LPR treatment.

Methods

This is a pilot study in 15 participants with asthma. Those without evidence of LPR by SGI measurement were assigned to the observation arm. Those with LPR were assigned to the treatment arm and were treated with either standard-of-care LPR treatment (antacids and behavioral management) or a novel therapy (upper esophageal assist device).

Results

The SGI remained stable in individuals with asthma who underwent observation over 8 weeks. The SGI improved in participants with asthma treated for LPR (P = .024).

Conclusion

The SGI is a readily available clinical tool to assess the presence of LPR and monitor its therapy in asthma.

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来源期刊

Annals of Allergy Asthma & Immunology 医学-过敏

CiteScore

6.50

自引率

6.80%

发文量

437

审稿时长

33 days

期刊介绍： Annals of Allergy, Asthma & Immunology is a scholarly medical journal published monthly by the American College of Allergy, Asthma & Immunology. The purpose of Annals is to serve as an objective evidence-based forum for the allergy/immunology specialist to keep up to date on current clinical science (both research and practice-based) in the fields of allergy, asthma, and immunology. The emphasis of the journal will be to provide clinical and research information that is readily applicable to both the clinician and the researcher. Each issue of the Annals shall also provide opportunities to participate in accredited continuing medical education activities to enhance overall clinical proficiency.