Thermopsis turcica 的植物化学成分、抗菌、抗氧化和伤口愈合活性。

IF 1.8 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Gülçin Akdağ, Ömer Hazman, Laçine Aksoy, Mehmet Savrık, Ahmet Büyükben, Mustafa Abdullah Yılmaz, Oguz Cakir, Recep Kara
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引用次数: 0

摘要

该研究测定了用土鳖虫的枝、叶、花部分和地上部分制备的水提取物的抗氧化、抗菌、抗癌、伤口愈合活性和酚类物质概况。分析表明,混合提取物、花提取物和叶提取物的总酚类物质含量和总抗氧化能力较高。与 A549 细胞相比,这些提取物更能降低 HGF 细胞的活力。这表明提取物对 A549 细胞的抗癌活性较低。花提取物的伤口愈合率最高。通过 LC/ESI-MS/LC 分析发现,所有提取物中都含有高浓度的奎宁酸、环糖苷和木犀草素。结果表明,该物种的花提取物是最关键的部分,具有抗氧化、抗菌、细胞毒性和伤口愈合特性。叶提取物和混合提取物的抗氧化性和抗菌性突出,而树枝提取物对伤口愈合有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phytochemical composition, antimicrobial, antioxidant, and wound healing activities of Thermopsis turcica.

The antioxidant, antimicrobial, anticarcinogenic, wound healing activities and phenolic substance profile of aqueous extracts prepared using branch, leaf, flower parts and above-ground parts of Thermopsis turcica were determined in the study. The analyses indicate that the total phenolic substance contents and total antioxidant status are higher in the mix, flower, and leaf extracts. The extracts reduced cell viability in HGF cells more than in A549 cells. It shows that the extract has low anticarcinogenic activity in A549 cells. Flower extract had the highest wound closure rate. Quinic acid, cyranoside and luteolin were found in high concentrations in all extracts with LC/ESI-MS/LC analysis. It has been determined that the flower extract of the species is the most critical part showing antioxidant, antimicrobial, cytotoxic and wound healing properties. While the leaf and mix extracts stand out with their antioxidative and antimicrobial properties, the branch extract is effective in wound healing.

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来源期刊
CiteScore
4.10
自引率
5.00%
发文量
55
期刊介绍: A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.
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