Tracking of Infectious Diseases in Shahr-i Sokhta (Burnt City) during the Bronze Age (ca. 3200-2200 BCE) through Anemic Signs Observed in Excavated Human Skeletons.

Background: The intriguing area of paleopathology merges the disciplines of archeology and biological studies. Using this line of research, it is possible to identify diseases that have left skeletal traces in the past. In addition, diseases such as various anemia that occur in childhood, when bone tissue is soft and retains evidence, can be identified in ancient bones. Cribra orbitalia (Co), cribra cranii (Cc), and porotic hyperostosis (Ph) were ancient skeletal remains' most common degenerative anomalies.

Methods: Shahr-i Sokhta dated back to 3200-1800 BCE, is the subject of our research; it is located in Sistan and Baluchistan province (Iran). The research was done on the archaeological data collected during the MAIPS expeditions at Shahr-i Sokhta (2017-2021) kept at the storage of the excavated materials on the site. The skeletal remains were examined for bone abnormalities such as Co, Cc, and Ph. These symptoms were analyzed to obtain traces of anemia-related diseases at this site. Data has been utilized following the Data Collection Codebook.

Results: Ninety-six adults were studied while the anemic signs of CC and Co are respectively seen in 27/72 (37.5 %) and 10/57 (17; 5 %), and these samples have been kept for future analysis.

Conclusion: Bones may narrate a person's life, their gender and how old they were when they died besides the diseases they had. Some of the skeletons show signs of anemia, Classical paleopathology lets us to re-confirm studying diseases by further targeted sampling using molecular methods.