心血管代谢参数与高尿酸血症的患病率和关联性的性别差异:泰国那空那育省一项基于人口的横断面研究。

IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Iranian Journal of Public Health Pub Date : 2024-06-01
Chawin Suwanchatchai, Kitsarawut Khuancharee, Chantra Tanunyutthawongse, Sivaporn Wannaiampikul, Photsathorn Haetanurak
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引用次数: 0

摘要

背景:尽管高尿酸血症的发病率在不断上升,但针对中老年人群高尿酸血症的流行病学研究却十分有限。本研究旨在计算中老年人代谢参数和高尿酸血症(HUA)的患病率,并评估与性别相关的关联:这是一项基于人群的横断面研究,于 2018 年至 2019 年在泰国那空那育府的农村地区进行。我们招募了 780 名 40 岁及以上的受试者进行健康体检和检查调查。采用直接法估算了HUA的年龄标准化患病率。我们还进行了多元逻辑回归,以确定与 HUA 相关的潜在风险因素:HUA患病率为30.9%(男性为42%,女性为20%)。老年人患 HUA 的风险增加了 35%。研究发现,肥胖与男女 HUA 患病率的增加密切相关。高甘油三酯血症(男性增加 51%,女性增加 23%)和高空腹血糖(男性增加 90%,女性增加 49%)也是导致男女 HUA 的相关风险因素。然而,低高密度脂蛋白仅与女性罹患 HUA 的风险增加 67% 有关:结论:与男性相比,女性HUA的年龄标准化患病率相对较低。本研究还显示,肥胖与男女 HUA 均有密切关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gender-Specific Differences in Prevalence and Association of Cardio-Metabolic Parameters and Hyperuricemia: A Population-Based Cross-Sectional Study, Nakhon Nayok, Thailand.

Background: Although the prevalence of HUA is increasing, epidemiologic studies on HUA in the middle-aged and elderly population are limited. The present study aimed to calculate the prevalence and evaluate the sex-related associations between metabolic parameters and hyperuricemia (HUA) among middle-aged and elderly adults.

Methods: This was a population-based cross-sectional study from 2018 to 2019 in rural areas of Nakhon Nayok Province, Thailand. We enrolled 780 subjects aged 40 yr and over for health check-ups and examination surveys. The age-standardized prevalence of HUA was estimated by the direct method. A multiple logistic regression was performed to identify the potential risk factors associated with HUA.

Results: The prevalence of HUA were 30.9% (42% in males vs. 20% in females). Elderly adults were associated with a 35% increase in the risk of HUA. Obesity was found to be strongly associated with an increased prevalence of HUA in both sexes. Hypertriglyceridemia (51% increase in males vs. 23% increase in females), and high fasting glucose (90% increase in males vs. 49% increase in females) were also associated risk factors for HUA in both sexes. However, low high-density lipoprotein was only associated with a 67% increase in the risk of HUA in females.

Conclusion: The age-standardized prevalence of HUA among females is relatively lower than in males. This study also revealed that obesity is strongly associated with HUA in both sexes.

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来源期刊
Iranian Journal of Public Health
Iranian Journal of Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.20
自引率
7.10%
发文量
300
审稿时长
3-8 weeks
期刊介绍: Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above men­tioned research areas.
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