在对 I 级和 II 级牙周病患者进行洗牙和根面平整治疗后,对一种由洗必泰和赛美诺配制的新型漱口水进行评估。

IF 1.8 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
P Hermida-Cabrera, F Aguilera, F Vivancos-Cuadras, L Ferrá-Domingo, D Torres-Lagares, J Gutiérrez-Pérez, T Pereira-Riveros, T-V Serrera-Figallo, M Baus-Domínguez
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引用次数: 0

摘要

背景:牙周病(PD)是一种影响牙齿支持组织的多因素慢性炎症性疾病。据世界卫生组织预测,到 2022 年,严重的牙周病将影响全球约 19% 的成年人。其风险因素包括生物膜中牙周致病菌的存在和宿主免疫系统的易感性等。早产的定义是胎龄 37 周前出生的婴儿。早产也是多因素造成的,与宫内和宫外感染等风险因素有关。孕妇牙周病有可能通过血源性途径或炎症介质的存在和干预增加早产风险:通过对2014年至2024年的现有科学文章进行系统回顾,选择了5项随机临床试验,共包括1984名确诊患有牙周病的孕妇。其中一半患者接受了非手术治疗,另一半患者没有接受治疗,目的是评估牙周病和/或其治疗与早产发生之间可能存在的关联。利用科克伦 "RoB 2 "工具评估了偏倚风险,最后进行了荟萃分析,以比较所选研究的结果:结果:有四篇文章显示,非手术牙周治疗作为早产预防措施的趋势得到了支持。这些文章占总篇幅的 92.2%,其余 7.85%的文章均不赞成这种治疗方法。然而,没有一篇文章显示出具有统计学意义的结果:结论:孕妇牙周病与早产发生率之间没有明显的联系。另一方面,怀孕期间进行非手术牙周治疗作为降低早产发生率的一种措施,有稍微有利的趋势,但在统计学上并不显著。要想得到确切的答案,还需要更多采用类似研究和设计参数的随机临床试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of a new mouthwash formulated with Chlorhexidine and Cymenol after a scaling and root planing treatment in grade I and II periodontal patients.

Background: Periodontal disease is a multifactorial pathology whose treatment protocol is becoming increasingly standardized, relying, among others, on adjuvant therapies. This study aims to determine the efficacy of a new chlorhexidine compound compared with the gold standard 0.12% chlorhexidine during periodontal maintenance of a patient with periodontitis grade I or II after scaling and root planing treatment.

Material and methods: A parallel, randomized, double-blind clinical trial with two arms: (A) treatment with 0.12% chlorhexidine mouthwash; (B) treatment with new chlorhexidine mouthwash containing O-Cymen-5-Ol. The patient was examined: (D0) initial examination, (D7) clinical examination one week after treatment, (D14) clinical examination two weeks after treatment and (D28) clinical examination three weeks after treatment. They are collecting the following data: Plaque index (PI), gingival index (GI), bleeding index (BoP), pocket depth (PS), and attachment loss (CAL).

Results: After a follow-up of 43 patients, no statistically significant differences were found between the groups at any of the times or for any of the parameters evaluated, meeting the predefined criteria of non-inferiority.

Conclusions: The new chlorhexidine mouthwash proved to be non-inferior to 0.12% chlorhexidine in terms of efficacy during short-term periodontal maintenance after scaling and root planing.

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来源期刊
Medicina Oral Patologia Oral Y Cirugia Bucal
Medicina Oral Patologia Oral Y Cirugia Bucal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
4.60
自引率
0.00%
发文量
52
审稿时长
3-8 weeks
期刊介绍: 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology
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